Abstract Beta‐hydroxy‐beta‐methylbutyrate (HMB) is a metabolite of the essential amino
acid leucine that has been reported to have anabolic effects on protein metabolism. The …

SARS-CoV-2 infection affects multiple organs owing to the ubiquitous distribution of its target
receptor ACE-2. 1 Increasing interest has been paid to the postacute phase of COVID-19 …

Both regular exercise training and beta-hydroxy-beta-methylbutyrate (HMB)
supplementation are shown as effective treatments to delay or reverse frailty and reduce …

Introduction Chronic obstructive pulmonary disease (COPD) is associated with an intestinal
leak and neuromuscular junction (NMJ) degradation, which contributes to physical …

The older diseased population might benefit from dietary HMB because of its established
positive properties as well as its long lasting (pharmacological) effect. In addition to …

Aging is associated with cognitive decline. Herein, we studied a large cohort of old age and
young adult male rats and confirmed that, as a group, old rats display poorer spatial learning …

Objectives To investigate the synergist effects of exercise and β-hydroxy β-methylbutyrate
(HMB) supplementation on disability, cognitive and physical function, and muscle power in …

The purpose of this review is to discuss the structural and physiological changes that
underlie age-related neuromuscular dysfunction and to summarize current evidence on the …

Objectives: Normal aging results in cognitive decline and nutritional interventions have been
suggested as potential approaches for mitigating these deficits. Here, we used rats to …

Sex differences occur in the structure and function of the rat cerebral cortex and
hippocampus, which can change from the juvenile period through old age. Although the …