Attributable to its late diagnosis, early metastasis, and poor prognosis, pancreatic cancer
remains one of the most lethal diseases worldwide. Unlike other solid tumors, pancreatic …

Epithelial-to-mesenchymal transition (EMT) and its reversed process, mesenchymal-to-
epithelial transition (MET), are fundamental processes in embryonic development and tissue …

The epithelial–mesenchymal transition (EMT) is a developmental program that enables
stationary epithelial cells to gain the ability to migrate and invade as single cells. Tumor cells …

The mammary gland is a compound, branched tubuloalveolar structure and a major
characteristic of mammals. The mammary gland has evolved from epidermal apocrine …

The complex cross‐talk of intricate intercellular signaling networks between the tumor and
stromal cells promotes cancer progression. Hypoxia is one of the most common conditions …

Claudins are tight junction membrane proteins that are expressed in epithelia and
endothelia and form paracellular barriers and pores that determine tight junction …

Purpose: Epithelial–mesenchymal transition (EMT) has been associated with metastatic
spread and EGF receptor (EGFR) inhibitor resistance. We developed and validated a robust …

Highly pathogenic avian H5N1 influenza A viruses occasionally infect humans, but currently
do not transmit efficiently among humans. The viral haemagglutinin (HA) protein is a known …

Metastasis is the leading reason for the resultant mortality of patients with cancer. The past
few decades have witnessed remarkable progress in understanding the molecular and …

Transforming growth factor-beta (TGF-β) plays multiple homeostatic roles in the regulation of
inflammation, proliferation, differentiation and would healing of various tissues. Many studies …