Antibody-mediated neutralization of SARS-CoV-2

H Gruell, K Vanshylla, T Weber, CO Barnes, C Kreer… - Immunity, 2022 - cell.com
Neutralizing antibodies can block infection, clear pathogens, and are essential to provide
long-term immunity. Since the onset of the pandemic, SARS-CoV-2 neutralizing antibodies …

Engineering ACE2 decoy receptors to combat viral escapability

T Arimori, N Ikemura, T Okamoto, J Takagi… - Trends in …, 2022 - cell.com
Decoy receptor proteins that trick viruses to bind to them should be resistant to viral escape
because viruses that require entry receptors cannot help but bind decoy receptors …

Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice

AC Hunt, JB Case, YJ Park, L Cao, K Wu… - Science translational …, 2022 - science.org
New variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continue to
arise and prolong the coronavirus disease 2019 (COVID-19) pandemic. Here, we used a …

Moderate DNA and high SARS-CoV-2 spike protein affinity of oxidovanadium (IV) complexes of 2-furoic acid hydrazones: In silico and in vitro approach

A Zahirović, B Tüzün, S Hadžalić, I Osmanković… - Journal of molecular …, 2023 - Elsevier
The interaction of five neutral heteroleptic octahedral paramagnetic mononuclear
oxidovanadium (IV) complexes of general composition [V IV O (bpy) L], where L is a …

[HTML][HTML] COVID-19: prevención, diagnóstico y tratamiento. Recomendaciones de un grupo multidisciplinario

FJ Ortiz-Ibarra, JA Simón-Campos… - Medicina Interna de …, 2022 - medigraphic.com
Antecedentes: La infección por SARS-CoV-2, causante de la COVID-19 ha impactado al
mundo entero debido a su extensa y rápida propagación. En los dos últimos años se han …

Outpatient treatment options to address the SARS-CoV-2 variant Omicron

MW McCarthy - Expert Review of Anti-infective Therapy, 2022 - Taylor & Francis
ABSTRACT Introduction On 26 November 2021, the World Health Organization's Technical
Advisory Group on SARS-CoV-2 Virus Evolution designated PANGO lineage B. 1.1. 529 a …

The highly conserved stem-loop II motif is dispensable for SARS-CoV-2

H Jiang, A Joshi, T Gan, AB Janowski, C Fujii… - Journal of …, 2023 - Am Soc Microbiol
The stem-loop II motif (s2m) is an RNA structural element that is found in the 3′
untranslated region (UTR) of many RNA viruses, including severe acute respiratory …

mRNA-1273 and Ad26. COV2. S vaccines protect against the B. 1.621 variant of SARS-CoV-2

TL Darling, B Ying, B Whitener, LA VanBlargan… - Med, 2022 - cell.com
Background Since the emergence of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) in 2019, viral variants with greater transmissibility or immune-evasion …

Safety and immunogenicity of a booster vaccination by CoronaVac or BNT162b2 in previously two-dose inactivated virus vaccinated individuals with negative …

KTW Lai, EYT Lai Wan Loong, TLH Fung, LWP Luk… - Vaccines, 2022 - mdpi.com
COVID-19 has swept across the globe since 2019 and repeated waves of infection have
been caused by different variants of the original SARS-CoV-2 (wild type), with the Omicron …

Prototype mRNA vaccines imprint broadly neutralizing human serum antibodies after Omicron variant-matched boosting

CY Liang, S Raju, Z Liu, Y Li, GA Arunkumar, JB Case… - BioRxiv, 2024 - biorxiv.org
Immune imprinting is a phenomenon in which an individual's prior antigenic experiences
influence responses to subsequent infection or vaccination. Here, using antibody depletion …