MRI in the diagnosis and monitoring of multiple sclerosis: an update

MP Wattjes, MD Steenwijk, M Stangel - Clinical neuroradiology, 2015 - Springer
Magnetic resonance imaging (MRI) is the most powerful tool for the early (differential)
diagnosis of multiple sclerosis (MS) and has been part of the International Panel criteria …

The chameleon of neuroinflammation: magnetic resonance imaging characteristics of natalizumab-associated progressive multifocal leukoencephalopathy

MP Wattjes, ND Richert, J Killestein… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Natalizumab is a monoclonal antibody against α4-integrin approved for the treatment of
multiple sclerosis (MS) due to a positive effect on clinical and magnetic resonance imaging …

Increased cortical grey matter lesion detection in multiple sclerosis with 7 T MRI: a post-mortem verification study

ID Kilsdonk, LE Jonkman, R Klaver, SJ van Veluw… - Brain, 2016 - academic.oup.com
The relevance of cortical grey matter pathology in multiple sclerosis has become
increasingly recognized over the past decade. Unfortunately, a large part of cortical lesions …

Improved differentiation between MS and vascular brain lesions using FLAIR* at 7 Tesla

ID Kilsdonk, MP Wattjes, A Lopez-Soriano… - European …, 2014 - Springer
Objectives To investigate whether a new magnetic resonance image (MRI) technique called
T2*-weighted fluid attenuation inversion recovery (FLAIR*) can differentiate between …

Optic radiation damage in multiple sclerosis is associated with visual dysfunction and retinal thinning–an ultrahigh-field MR pilot study

T Sinnecker, T Oberwahrenbrock, I Metz… - European …, 2015 - Springer
Objective To investigate posterior visual pathway damage in multiple sclerosis using
ultrahigh-field magnetic resonance imaging (MRI) at 7 Tesla (7 T), and to determine its …

Ultrahigh‐field MR (7 T) imaging of brain lesions in neuromyelitis optica

I Kister, J Herbert, Y Zhou, Y Ge - Multiple Sclerosis …, 2013 - Wiley Online Library
Background. Brain lesions are common in neuromyelitis optica spectrum disorder (NMOsd)
and may resemble lesions of multiple sclerosis (MS). Objectives. To describe the imaging …

Clinical application of multi-contrast 7-T MR imaging in multiple sclerosis: increased lesion detection compared to 3 T confined to grey matter

WL de Graaf, ID Kilsdonk, A Lopez-Soriano… - European …, 2013 - Springer
Abstract Objectives Seven-Tesla MRI demonstrated new pathological features of multiple
sclerosis (MS) using T2*-weighted sequences. However, a clinical MRI protocol at 7 T has …

Diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy using MRI

MP Wattjes, F Barkhof - Current Opinion in Neurology, 2014 - journals.lww.com
MRI is the most powerful method in the detection of natalizumab-associated PML by
showing imaging patterns helpful in the differentiation between PML and multiple sclerosis …

Morphological features of MS lesions on FLAIR* at 7 T and their relation to patient characteristics

ID Kilsdonk, A Lopez-Soriano, JPA Kuijer… - Journal of …, 2014 - Springer
Recently, a new MRI technique was developed at 3 Tesla (T), called fluid attenuated
inversion recovery*(FLAIR*). In this study, we implemented FLAIR* in an existing MS cohort …

Perivascular spaces in MS patients at 7 Tesla MRI: a marker of neurodegeneration?

ID Kilsdonk, MD Steenwijk… - Multiple Sclerosis …, 2015 - journals.sagepub.com
Background: Virchow-Robin spaces (VRS) are associated with vascular and
neurodegenerative disease. In multiple sclerosis (MS), VRS have been associated with …