Role of probiotics in the management of COVID-19: A computational perspective
Coronavirus disease 2019 (COVID-19) was declared a pandemic at the beginning of 2020,
causing millions of deaths worldwide. Millions of vaccine doses have been administered …
causing millions of deaths worldwide. Millions of vaccine doses have been administered …
[HTML][HTML] Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification
The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the
effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The …
effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The …
[HTML][HTML] Structural basis of SARS-CoV-2 3CLpro and anti-COVID-19 drug discovery from medicinal plants
The recent pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has
raised global health concerns. The viral 3-chymotrypsin-like cysteine protease (3CL pro) …
raised global health concerns. The viral 3-chymotrypsin-like cysteine protease (3CL pro) …
Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeutic drug target using a computational approach
Abstract Background The Severe acute respiratory syndrome-related coronavirus 2 (SARS-
CoV-2) outbreak originating in Wuhan, China, has raised global health concerns and the …
CoV-2) outbreak originating in Wuhan, China, has raised global health concerns and the …
Identification of potential inhibitors of SARS-CoV-2 main protease from Aloe vera compounds: A molecular docking study
SARS-CoV-2 is the pathogen agent of the new corona virus disease that appeared at the
end of 2019 in China. There is, currently, no effective treatment against COVID-19. We report …
end of 2019 in China. There is, currently, no effective treatment against COVID-19. We report …
[HTML][HTML] Promising terpenes as SARS-CoV-2 spike receptor-binding domain (RBD) attachment inhibitors to the human ACE2 receptor: Integrated computational …
The spike protein receptor binding domain (S-RBD) is a necessary corona-viral protein for
binding and entry of coronaviruses (COVs) into the host cells. Hence, it has emerged as an …
binding and entry of coronaviruses (COVs) into the host cells. Hence, it has emerged as an …
Designing of a next generation multiepitope based vaccine (MEV) against SARS-COV-2: Immunoinformatics and in silico approaches
Coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
coronavirus 2 (SARS-COV-2) is a significant threat to global health security. Till date, no …
coronavirus 2 (SARS-COV-2) is a significant threat to global health security. Till date, no …
Pharmacoinformatics and molecular dynamics simulation studies reveal potential covalent and FDA-approved inhibitors of SARS-CoV-2 main protease 3CLpro
The SARS-CoV-2 was confirmed to cause the global pandemic of coronavirus disease 2019
(COVID-19). The 3-chymotrypsin-like protease (3CLpro), an essential enzyme for viral …
(COVID-19). The 3-chymotrypsin-like protease (3CLpro), an essential enzyme for viral …
In vitro and in silico anti-dengue activity of compounds obtained from Psidium guajava through bioprospecting
AI Trujillo-Correa, DC Quintero-Gil… - … and alternative medicine, 2019 - Springer
Background For decades, bioprospecting has proven to be useful for the identification of
compounds with pharmacological potential. Considering the great diversity of Colombian …
compounds with pharmacological potential. Considering the great diversity of Colombian …
Reverse vaccinology assisted designing of multiepitope-based subunit vaccine against SARS-CoV-2
M Tahir ul Qamar, F Shahid, S Aslam… - Infectious diseases of …, 2020 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) linked with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) cause severe illness and life-threatening …
respiratory syndrome coronavirus 2 (SARS-CoV-2) cause severe illness and life-threatening …