Water-soluble conjugated polymers for imaging, diagnosis, and therapy
Conjugated polymers (CPs) are characterized by a delocalized electronic structure that
exhibits efficient coupling between optoelectronic segments. Excitons can be efficiently …
exhibits efficient coupling between optoelectronic segments. Excitons can be efficiently …
Nanoparticles–known and unknown health risks
PHM Hoet, I Brüske-Hohlfeld, OV Salata - Journal of nanobiotechnology, 2004 - Springer
Manmade nanoparticles range from the well-established multi-ton production of carbon
black and fumed silica for applications in plastic fillers and car tyres to microgram quantities …
black and fumed silica for applications in plastic fillers and car tyres to microgram quantities …
In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis
D Fischer, Y Li, B Ahlemeyer, J Krieglstein, T Kissel - Biomaterials, 2003 - Elsevier
A comparative in vitro cytotoxicity study with different water-soluble, cationic
macromolecules which have been described as gene delivery systems was performed …
macromolecules which have been described as gene delivery systems was performed …
Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
T Merdan, J Kopec̆ek, T Kissel - Advanced drug delivery reviews, 2002 - Elsevier
Gene and antisense/ribozyme therapy possesses tremendous potential for the successful
treatment of genetically based diseases, such as cancer. Several cancer gene therapy …
treatment of genetically based diseases, such as cancer. Several cancer gene therapy …
Polylysine-based transfection systems utilizing receptor-mediated delivery
Receptor-mediated gene transfer is a promising gene delivery technique. It employs a DNA-
binding polycation, such as polylysine, to compact plasmid DNA to a size that can be taken …
binding polycation, such as polylysine, to compact plasmid DNA to a size that can be taken …
[HTML][HTML] Effects of the chemical structure and the surface properties of polymeric biomaterials on their biocompatibility
YX Wang, JL Robertson, WB Spillman… - Pharmaceutical …, 2004 - Springer
Polymeric biomaterials have extensively been used in medicinal applications. However,
factors that determine their biocompatibility are still not very clear. This article reviews …
factors that determine their biocompatibility are still not very clear. This article reviews …
Macrophage uptake of core− shell nanoparticles surface modified with poly (ethylene glycol)
AS Zahr, CA Davis, MV Pishko - Langmuir, 2006 - ACS Publications
The in vitro uptake of core− shell nanoparticles encapsulated in a bio-macromolecular
nanoshell assembled from multilayered polyelectrolytes was studied. Sulfate modified …
nanoshell assembled from multilayered polyelectrolytes was studied. Sulfate modified …
In vitro cytotoxicity of macromolecules in different cell culture systems
S Choksakulnimitr, S Masuda, H Tokuda… - Journal of Controlled …, 1995 - Elsevier
The cytotoxic effect of various macromolecules in cultured bovine brain microvessel
endothelial cells, mouse peritoneal macrophages, and rat hepatocytes was analyzed by …
endothelial cells, mouse peritoneal macrophages, and rat hepatocytes was analyzed by …
Surface acetylation of polyamidoamine (PAMAM) dendrimers decreases cytotoxicity while maintaining membrane permeability
RB Kolhatkar, KM Kitchens, PW Swaan… - Bioconjugate …, 2007 - ACS Publications
Improving the oral bioavailability of therapeutic compounds remains a challenging area of
research. Polyamidoamine (PAMAM) dendrimers are promising candidates for oral drug …
research. Polyamidoamine (PAMAM) dendrimers are promising candidates for oral drug …
Polylysine for skin regeneration: A review of recent advances and future perspectives
There have been several attempts to find promising biomaterials for skin regeneration,
among which polylysine (a homopolypeptide) has shown benefits in the regeneration and …
among which polylysine (a homopolypeptide) has shown benefits in the regeneration and …