Water-soluble conjugated polymers for imaging, diagnosis, and therapy

C Zhu, L Liu, Q Yang, F Lv, S Wang - Chemical reviews, 2012 - ACS Publications
Conjugated polymers (CPs) are characterized by a delocalized electronic structure that
exhibits efficient coupling between optoelectronic segments. Excitons can be efficiently …

Nanoparticles–known and unknown health risks

PHM Hoet, I Brüske-Hohlfeld, OV Salata - Journal of nanobiotechnology, 2004 - Springer
Manmade nanoparticles range from the well-established multi-ton production of carbon
black and fumed silica for applications in plastic fillers and car tyres to microgram quantities …

In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis

D Fischer, Y Li, B Ahlemeyer, J Krieglstein, T Kissel - Biomaterials, 2003 - Elsevier
A comparative in vitro cytotoxicity study with different water-soluble, cationic
macromolecules which have been described as gene delivery systems was performed …

Prospects for cationic polymers in gene and oligonucleotide therapy against cancer

T Merdan, J Kopec̆ek, T Kissel - Advanced drug delivery reviews, 2002 - Elsevier
Gene and antisense/ribozyme therapy possesses tremendous potential for the successful
treatment of genetically based diseases, such as cancer. Several cancer gene therapy …

Polylysine-based transfection systems utilizing receptor-mediated delivery

W Zauner, M Ogris, E Wagner - Advanced drug delivery reviews, 1998 - Elsevier
Receptor-mediated gene transfer is a promising gene delivery technique. It employs a DNA-
binding polycation, such as polylysine, to compact plasmid DNA to a size that can be taken …

[HTML][HTML] Effects of the chemical structure and the surface properties of polymeric biomaterials on their biocompatibility

YX Wang, JL Robertson, WB Spillman… - Pharmaceutical …, 2004 - Springer
Polymeric biomaterials have extensively been used in medicinal applications. However,
factors that determine their biocompatibility are still not very clear. This article reviews …

Macrophage uptake of core− shell nanoparticles surface modified with poly (ethylene glycol)

AS Zahr, CA Davis, MV Pishko - Langmuir, 2006 - ACS Publications
The in vitro uptake of core− shell nanoparticles encapsulated in a bio-macromolecular
nanoshell assembled from multilayered polyelectrolytes was studied. Sulfate modified …

In vitro cytotoxicity of macromolecules in different cell culture systems

S Choksakulnimitr, S Masuda, H Tokuda… - Journal of Controlled …, 1995 - Elsevier
The cytotoxic effect of various macromolecules in cultured bovine brain microvessel
endothelial cells, mouse peritoneal macrophages, and rat hepatocytes was analyzed by …

Surface acetylation of polyamidoamine (PAMAM) dendrimers decreases cytotoxicity while maintaining membrane permeability

RB Kolhatkar, KM Kitchens, PW Swaan… - Bioconjugate …, 2007 - ACS Publications
Improving the oral bioavailability of therapeutic compounds remains a challenging area of
research. Polyamidoamine (PAMAM) dendrimers are promising candidates for oral drug …

Polylysine for skin regeneration: A review of recent advances and future perspectives

P Zarrintaj, S Ghorbani, M Barani… - Bioengineering & …, 2022 - Wiley Online Library
There have been several attempts to find promising biomaterials for skin regeneration,
among which polylysine (a homopolypeptide) has shown benefits in the regeneration and …