Mechanisms, hallmarks, and implications of stem cell quiescence

IJ Cho, PPW Lui, J Obajdin, F Riccio, W Stroukov… - Stem cell reports, 2019 - cell.com
Cellular quiescence is a dormant but reversible cellular state in which cell-cycle entry and
proliferation are prevented. Recent studies both in vivo and in vitro demonstrate that …

Skeletal muscle stem cells in comfort and stress

B Evano, S Tajbakhsh - NPJ Regenerative medicine, 2018 - nature.com
Investigations on developmental and regenerative myogenesis have led to major advances
in decrypting stem cell properties and potential, as well as their interactions within the …

Regenerative proliferation of differentiated cells by mTORC 1‐dependent paligenosis

SG Willet, MA Lewis, ZF Miao, D Liu, MD Radyk… - The EMBO …, 2018 - embopress.org
In 1900, Adami speculated that a sequence of context‐independent energetic and structural
changes governed the reversion of differentiated cells to a proliferative, regenerative state …

Cellular quiescence in budding yeast

S Sun, D Gresham - Yeast, 2021 - Wiley Online Library
Cellular quiescence, the temporary and reversible exit from proliferative growth, is the
predominant state of all cells. However, our understanding of the biological processes and …

Quiescence entry, maintenance, and exit in adult stem cells

K Mohammad, P Dakik, Y Medkour… - International Journal of …, 2019 - mdpi.com
Cells of unicellular and multicellular eukaryotes can respond to certain environmental cues
by arresting the cell cycle and entering a reversible state of quiescence. Quiescent cells do …

The cell biology of quiescent yeast–a diversity of individual scenarios

I Sagot, D Laporte - Journal of Cell Science, 2019 - journals.biologists.com
Most cells, from unicellular to complex organisms, spend part of their life in quiescence, a
temporary non-proliferating state. Although central for a variety of essential processes …

Single cell derived spheres of umbilical cord mesenchymal stem cells enhance cell stemness properties, survival ability and therapeutic potential on liver failure

Y Qiao, Z Xu, Y Yu, S Hou, J Geng, T Xiao, Y Liang… - Biomaterials, 2020 - Elsevier
Umbilical cord mesenchymal stem cells (UCMSCs) have shown great potentials in
regenerative medicine for their extensive sources, multilineage differentiation potential, low …

Nitrogen-dependent coordination of cell cycle, quiescence and TAG accumulation in Chlamydomonas

T Takeuchi, C Benning - Biotechnology for Biofuels, 2019 - Springer
Microalgae hold great promises as sustainable cellular factories for the production of
alternative fuels, feeds, and biopharmaceuticals for human health. While the biorefinery …

The CalcR-PKA-Yap1 axis is critical for maintaining quiescence in muscle stem cells

L Zhang, Y Noguchi, H Nakayama, T Kaji, K Tsujikawa… - Cell reports, 2019 - cell.com
Quiescence is a fundamental property of adult stem cells. Recent evidence indicates that
quiescence is not a default state but requires active signaling that prevents accidental or …

Transcriptional reprogramming in cellular quiescence

B Roche, B Arcangioli, R Martienssen - RNA biology, 2017 - Taylor & Francis
Most cells in nature are not actively dividing, yet are able to return to the cell cycle given the
appropriate environmental signals. There is now ample evidence that quiescent G0 cells are …