Lipoprotein receptors in the nervous system

J Herz, HH Bock - Annual review of biochemistry, 2002 - annualreviews.org
▪ Abstract The low-density–lipoprotein (LDL) receptor family is an evolutionarily ancient
gene family of structurally closely related cell-surface receptors. Members of the family are …

Ammon's horn sclerosis: a maldevelopmental disorder associated with temporal lobe epilepsy

IB MD, MT MRCPath, OD Wiestler - Brain pathology, 2002 - Wiley Online Library
Ammon's horn sclerosis (AHS) is the major neuropathological substrate in patients with
temporal lobe epilepsy (TLE). Histopathological hallmarks include segmental loss of …

Reelin expression and glycosylation patterns are altered in Alzheimer's disease

A Botella-López, F Burgaya, R Gavín… - Proceedings of the …, 2006 - National Acad Sciences
Reelin is a glycoprotein that is essential for the correct cytoarchitectonic organization of the
developing CNS. Its function in the adult brain is less understood, although it has been …

Embryonic and early fetal development of the human neocortex

G Meyer, JP Schaaps, L Moreau… - Journal of …, 2000 - Soc Neuroscience
Early corticogenesis was studied in human embryos and early fetuses from Carnegie stages
16 to 22 (5–8 gestational weeks) by using immunohistochemistry for Reelin (Reln), calretinin …

Cdk5 on the brain

DS Smith, PL Greer, LH Tsai - 2001 - AACR
Mammalian brains are highly compartmentalized into groups of functionally specialized
neurons. Cell migration and neurite outgrowth must be tightly orchestrated to achieve this …

The evolution of cortical development. An hypothesis based on the role of the Reelin signaling pathway

I Bar, CL De Rouvroit, AM Goffinet - Trends in neurosciences, 2000 - cell.com
Expression of the genes encoding Reelin and Dab1 during cortical development in turtle,
lizard, chick and mammals correlates with architectonic patterns. In all species, Reelin is …

β-amyloid controls altered Reelin expression and processing in Alzheimer's disease

A Botella-López, I Cuchillo-Ibáñez, T Cotrufo… - Neurobiology of …, 2010 - Elsevier
Reelin is a glycoprotein that modulates synaptic function and plasticity in the mature brain,
thereby favouring memory formation. We recently reported altered cerebral Reelin …

Identification of a human follicular dendritic cell molecule that stimulates germinal center B cell growth

L Li, X Zhang, S Kovacic, AJ Long, K Bourque… - The Journal of …, 2000 - rupress.org
The initial interaction between B cells and follicular dendritic cells (FDCs) appears to be
essential for germinal center (GC) formation. To identify molecules regulating this …

Conserved and divergent patterns of Reelin expression in the zebrafish central nervous system

A Costagli, M Kapsimali, SW Wilson… - Journal of Comparative …, 2002 - Wiley Online Library
The protein Reelin is suggested to function in cell–cell interactions and in mediating
neuronal migrations in layered central nervous system structures. With the aim of shedding …

Reelin in Alzheimer's disease, increased levels but impaired signaling: when more is less

I Cuchillo-Ibanez, V Balmaceda… - Journal of …, 2016 - content.iospress.com
In the continuing search for proteins that play a role in Alzheimer's disease (AD) and that are
related to the pathological hallmarks, those that influence cognitive function and that …