Abundant mycolic acids are the hallmark of the mycobacterial cell wall. The biosynthesis of
mycolic acids fulfilled by type I (Fas-I) and type II (Fas-II) synthase systems necessitates long …

A simple and convenient CuI/2-pyridonate catalytic system for the oxidative amidation of
aldehydes with secondary amines has been developed. With this system, a variety of useful …

A major limitation in current molecular docking method is that of failure to account for
receptor flexibility. Herein we report multiple receptor conformers based molecular docking …

Tuberculosis (TB) is one of the leading causes of death worldwide. The development of new
anti-tubercular drugs is required as resistant strains of M. tuberculosis to various first-line …

The Mycobacterium tuberculosis NADH-dependent enoyl-acyl carrier protein reductase (Mt
InhA) catalyzes hydride transfer to long-chain enoyl thioester substrates. Mt InhA is a …

This study presents the synthesis of nineteen 1-(substitutedbenzoyl)-4-benzhydrylpiperazine
and 1-[(substitutedphenyl) sulfonyl]-4-benzhydrylpiperazine derivatives. In vitro cytotoxic …

Synthesis and cytotoxic activities of 32 benzhydrylpiperazine derivatives with carboxamide
and thioamide moieties were reported. In vitro cytotoxic activities of compounds were …

Synthesis of amides through an oxidative amidation of tetrazoles with aldehydes under
transition-metal-free conditions - RSC Advances (RSC Publishing) DOI:10.1039/C4RA07658C …

A mild and efficient protocol for oxidative amidation of diverse aldehydes with amines was
developed using 3 mol% tris (pentafluorophenyl) borane and tert-butyl hydroperoxide to …

Abstract N‐benzhydrylpiperazine and 1, 3, 4‐oxadiazoles are pharmacologically active
scaffolds which exhibits significant inhibitory growth effects against various cancer cells …