Functions of autophagy in chloroplast protein degradation and homeostasis

C Wan, Q Ling - Frontiers in Plant Science, 2022 - frontiersin.org
Chloroplasts are defining organelles in plant and algae, which carried out various critical
metabolic processes, including photosynthesis. Roles of chloroplast protein homeostasis in …

Ppm1b negatively regulates necroptosis through dephosphorylating Rip3

W Chen, J Wu, L Li, Z Zhang, J Ren, Y Liang… - Nature cell …, 2015 - nature.com
The auto-phosphorylation of murine receptor-interacting protein 3 (Rip3) on Thr 231 and Ser
232 in the necrosome is required to trigger necroptosis. However, how Rip3 phosphorylation …

Regulators of G-protein-signaling proteins: negative modulators of G-protein-coupled receptor signaling

GE Woodard, I Jardin, A Berna-Erro, GM Salido… - International review of …, 2015 - Elsevier
Regulators of G-protein-signaling (RGS) proteins are a category of intracellular proteins that
have an inhibitory effect on the intracellular signaling produced by G-protein-coupled …

PI3K mediates tumor necrosis factor induced-necroptosis through initiating RIP1-RIP3-MLKL signaling pathway activation

S Hu, X Chang, H Zhu, D Wang, G Chen - Cytokine, 2020 - Elsevier
Necroptosis is a recently identified programmed cell death, which is initiated by receptor-
interacting serine/threonine-protein kinase 1 (RIP1), RIP3 and mixed-lineage kinase domain …

A diagnostic model for Alzheimer's disease based on blood levels of autophagy-related genes

Q Qin, Z Gu, F Li, Y Pan, TX Zhang, Y Fang… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a common neurodegenerative disease. The major problems that
exist in the diagnosis of AD include the costly examinations and the high-invasive sampling …

The adhesion G protein‐coupled receptor VLGR1/ADGRV1 controls autophagy

J Linnert, BE Güler, J Krzysko… - Basic & clinical …, 2023 - Wiley Online Library
Abstract VLGR1/ADGRV1 (very large G protein‐coupled receptor‐1) is the largest known
adhesion G protein‐coupled receptor. Mutations in VLGR1/ADGRV1 cause Usher syndrome …

Off‐target inhibition of NGLY1 by the polycaspase inhibitor Z‐VAD‐fmk induces cellular autophagy

SH Needs, MD Bootman, JE Grotzke… - The FEBS …, 2022 - Wiley Online Library
The polycaspase inhibitor Z‐VAD‐fmk acts as an inhibitor of peptide: N‐glycanase (NGLY1),
an endoglycosidase which cleaves N‐linked glycans from glycoproteins exported from the …

Significant prognostic value of the autophagy-related gene P4HB in bladder urothelial carcinoma

L Lyu, W Xiang, F Zheng, T Huang, Y Feng… - Frontiers in …, 2020 - frontiersin.org
While hundreds of consistently altered autophagy-related genes (ARGs) have been
identified in cancers, their prognostic value in bladder urothelial carcinoma (BUC) remains …

[HTML][HTML] G-Protein Signaling Protein-17 (RGS17) is upregulated and promotes tumor growth and migration in human colorectal carcinoma

L Li, HS Luo - Oncology Research, 2018 - ncbi.nlm.nih.gov
Colorectal carcinoma is one of the leading causes of cancer-related deaths and has a high
tendency for metastasis, which makes it a priority to find novel methods to diagnose and …

[HTML][HTML] Low expression of GNAI3 predicts poor prognosis in patients with HCC

G Chen, X Li, G He, Z Yu, J Luo, J He… - International Journal of …, 2015 - ncbi.nlm.nih.gov
Purposes: This study was performed with an aim to explain the underlying role of GNAI3 on
the prognosis of patients with HCC. Methods: The expression of GNAI3 at protein level was …