Acetylcholine (ACh) neurotransmitter of the cholinergic system in the brain is involved in
learning, memory, stress responses, and cognitive functioning. It is hydrolyzed into choline …

Natural cross-linkers are extensively employed due to their low toxicity and biocompatibility
benefits. Genipin acts as a precursor for producing blue colorants. The formation of these …

The emergence of drug-resistant bacterial and fungal pathogens has highlighted the urgent
need of innovative antimicrobial therapeutics. Transition metal complexes with biologically …

Alzheimer's disease is a most prevalent form of dementia all around the globe and currently
poses a significant challenge to the healthcare system. Currently available drugs only slow …

Triazole scaffolds, a series of 5-membered heterocycles, are well known for their high
efficacy, low toxicity, and superior pharmacokinetics. Alzheimer's disease (AD) is the first …

Considerable ingenuity has been shown in the recent years in the discovery of novel
xanthine oxidase (XO) inhibitors that fall outside the purine scaffold. The triazole nucleus …

A novel series of quinazoline-based agents bearing triazole-acetamides 8a-l were designed
and synthesized. All the obtained compounds were tested for in vitro cytotoxic activities …

Aim: The objective of the present study is to design and synthesize diverse piperazine-1, 2, 3-
triazole scaffolds as key pharmacophores possessing antimicrobial/anticancer activities …

Amyloid beta peptide (Aβ) and hyperphosphorylated neuronal tau proteins accumulate in
neurofibrillary tangles in Alzheimer's disease (AD), a chronic neurodegenerative illness …

Abstract A series of new 1, 2, 3-triazole derivatives was synthesized via a 1, 3-dipolar
cycloaddition reaction. Structures of the synthesized compounds were characterized by IR …