Myofibroblasts and fibrosis: mitochondrial and metabolic control of cellular differentiation
Cardiac fibrosis is mediated by the activation of resident cardiac fibroblasts, which
differentiate into myofibroblasts in response to injury or stress. Although myofibroblast …
differentiate into myofibroblasts in response to injury or stress. Although myofibroblast …
[HTML][HTML] Cardiovascular effects and benefits of exercise
MA Nystoriak, A Bhatnagar - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
It is widely accepted that regular physical activity is beneficial for cardiovascular health.
Frequent exercise is robustly associated with a decrease in cardiovascular mortality as well …
Frequent exercise is robustly associated with a decrease in cardiovascular mortality as well …
Long-term leisure-time physical activity intensity and all-cause and cause-specific mortality: a prospective cohort of US adults
Background: The 2018 physical activity guidelines for Americans recommend a minimum of
150 to 300 min/wk of moderate physical activity (MPA), 75 to 150 min/wk of vigorous …
150 to 300 min/wk of moderate physical activity (MPA), 75 to 150 min/wk of vigorous …
Exercise and the cardiovascular system: clinical science and cardiovascular outcomes
Substantial evidence has established the value of high levels of physical activity, exercise
training (ET), and overall cardiorespiratory fitness in the prevention and treatment of …
training (ET), and overall cardiorespiratory fitness in the prevention and treatment of …
Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship
Importance The 2008 Physical Activity Guidelines for Americans recommended a minimum
of 75 vigorous-intensity or 150 moderate-intensity minutes per week (7.5 metabolic …
of 75 vigorous-intensity or 150 moderate-intensity minutes per week (7.5 metabolic …
Metabolic coordination of physiological and pathological cardiac remodeling
Metabolic pathways integrate to support tissue homeostasis and to prompt changes in cell
phenotype. In particular, the heart consumes relatively large amounts of substrate not only to …
phenotype. In particular, the heart consumes relatively large amounts of substrate not only to …
Leisure-time running reduces all-cause and cardiovascular mortality risk
Background: Although running is a popular leisure-time physical activity, little is known
about the long-term effects of running on mortality. The dose-response relations between …
about the long-term effects of running on mortality. The dose-response relations between …
Prevalence of subclinical coronary artery disease in masters endurance athletes with a low atherosclerotic risk profile
A Merghani, V Maestrini, S Rosmini, AT Cox, H Dhutia… - Circulation, 2017 - Am Heart Assoc
Background: Studies in middle-age and older (masters) athletes with atherosclerotic risk
factors for coronary artery disease report higher coronary artery calcium (CAC) scores …
factors for coronary artery disease report higher coronary artery calcium (CAC) scores …
Dose of jogging and long-term mortality: the Copenhagen City Heart Study
P Schnohr, JH O'Keefe, JL Marott, P Lange… - Journal of the American …, 2015 - jacc.org
Background: People who are physically active have at least a 30% lower risk of death during
follow-up compared with those who are inactive. However, the ideal dose of exercise for …
follow-up compared with those who are inactive. However, the ideal dose of exercise for …
Physical activity in the prevention and treatment of coronary artery disease
EB Winzer, F Woitek, A Linke - Journal of the American Heart …, 2018 - Am Heart Assoc
In primary prevention, regular physical activity decreases the incidence of cardiovascular
disease. At the endothelial level, this decreased incidence was attributed to higher …
disease. At the endothelial level, this decreased incidence was attributed to higher …