Diabetic nephropathy (DN) often leads to end-stage renal disease. Oxidative stress
demonstrates a crucial act in the onset and progression of DN, which triggers various …

Esculetin is a coumarin compound, which belongs to the class of benzopyrone enriched in
various plants such as Sonchus grandifolius, Aesculus turbinata, etc. Free radicals lead to …

Diabetic retinopathy (DR) is a common complication of diabetes that can lead to progressive
vision loss. Regular surveillance with fundal photography, early diagnosis, and prompt …

Diabetes and its complications are closely correlated with chronic hyperglycemia, causing
severe oxidative stress and leading to glycation reaction with formation of advanced …

The accumulation of oxidative damage to DNA and other biomolecules plays an important
role in the etiology of aging and age-related diseases such as type 2 diabetes mellitus …

The comprehensive anabolic effects of insulin throughout the body, in addition to the control
of glycemia, include ensuring lipid homeostasis and anti-inflammatory modulation …

The polysaccharide AMP as one main bioactive component of Astragalus membranaceus
(Fisch.) Bunge was separated and characterized. The results showed that AMP was a typical …

A diabetic foot ulcer (DFU) is one of the major complications of diabetes. Wound healing
under diabetic conditions is often impaired. This is in part due to the excessive oxidative …

Aims There is a close link between oxidative stress, inflammation, and type 2 diabetes
mellitus (T2DM). Gentisic acid (GA) is a di-phenolic compound and an active metabolite of …

As important organelles of energetic and metabolism, changes in the dynamic state of
mitochondria affect the homeostasis of cellular metabolism. Mitochondrial dynamics include …