[HTML][HTML] Functions and dysfunctions of nitric oxide in brain

P Picón-Pagès, J Garcia-Buendia, FJ Munoz - Biochimica et Biophysica …, 2019 - Elsevier
Nitric oxide (NO) works as a retrograde neurotransmitter in synapses, allows the brain blood
flow and also has important roles in intracellular signaling in neurons from the regulation of …

On the clinical pharmacology of reactive oxygen species

AI Casas, C Nogales, HAM Mucke, A Petraina… - Pharmacological …, 2020 - Elsevier
Reactive oxygen species (ROS) have been correlated with almost every human disease. Yet
clinical exploitation of these hypotheses by pharmacological modulation of ROS has been …

Dysfunction of cerebrovascular endothelial cells: prelude to vascular dementia

F Wang, Y Cao, L Ma, H Pei, WD Rausch… - Frontiers in aging …, 2018 - frontiersin.org
Vascular dementia (VaD) is the second most common type of dementia after Alzheimer's
disease (AD), characterized by progressive cognitive impairment, memory loss, and thinking …

Mitostasis, calcium and free radicals in health, aging and neurodegeneration

JA Godoy, JA Rios, P Picón-Pagès… - Biomolecules, 2021 - mdpi.com
Mitochondria play key roles in ATP supply, calcium homeostasis, redox balance control and
apoptosis, which in neurons are fundamental for neurotransmission and to allow synaptic …

Fibrinogen and neuroinflammation during traumatic brain injury

N Sulimai, D Lominadze - Molecular neurobiology, 2020 - Springer
Many neurodegenerative diseases such as Alzheimer's disease (AD), multiple sclerosis,
and traumatic brain injury (TBI) are associated with systemic inflammation. Inflammation …

Breaking boundaries—coagulation and fibrinolysis at the neurovascular interface

S Bardehle, VA Rafalski, K Akassoglou - Frontiers in cellular …, 2015 - frontiersin.org
Blood proteins at the neurovascular unit (NVU) are emerging as important molecular
determinants of communication between the brain and the immune system. Over the past …

[HTML][HTML] The Dual Role of Amyloid Beta-Peptide in Oxidative Stress and Inflammation: Unveiling Their Connections in Alzheimer's Disease Etiopathology

H Fanlo-Ucar, P Picón-Pagès, V Herrera-Fernández… - Antioxidants, 2024 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease, and it is currently the
seventh leading cause of death worldwide. It is characterized by the extracellular …

[HTML][HTML] Thrombus composition and thrombolysis resistance in stroke

B Ho-Tin-Noé, JP Desilles, M Mazighi - Research and Practice in …, 2023 - Elsevier
A State of the Art lecture titled “Thrombus Composition and Thrombolysis Resistance in
Stroke” was presented at the ISTH Congress in 2022. Intravenous thrombolysis (IVT) …

[HTML][HTML] Anti-inflammatory and antioxidant actions of extracts from Rheum rhaponticum and Rheum rhabarbarum in human blood plasma and cells in vitro

O Liudvytska, M Bandyszewska, T Skirecki… - Biomedicine & …, 2023 - Elsevier
Rheum rhaponticum L.(rhapontic rhubarb) and Rheum rhabarbarum L.(garden rhubarb) are
edible and medicinal rhubarb species used for many centuries in traditional medicine. This …

[HTML][HTML] Effect of indoor air quality on the association of long-term exposure to low-level air pollutants with cognition in older adults

YC Chen, PI Hsieh, JK Chen, E Kuo, HL Yu… - Environmental …, 2023 - Elsevier
Background How indoor air quality affects the temporal associations of long-term exposure
to low-level air pollutants with cognition remains unclear. Methods This cohort study (2011 …