A hemolytic transfusion reaction (HTR) is the accelerated clearance or destruction of red
blood cells associated with a transfusion event. Causes of HTRs and differential diagnoses …

Enzymes catalyze biochemical reactions and play critical roles in human health and
disease. Enzyme variants and deficiencies can lead to variable expression of glycans, which …

Antibodies against red blood cell (RBC) alloantigens can increase morbidity and mortality
among transfusion recipients. However, alloimmunization rates can vary dramatically, as …

Passenger lymphocyte syndrome (PLS) is caused by the transfer of B-lymphocytes present
in the donor graft into the recipient circulation following solid organ or hematopoietic stem …

Erythrocyte alloimmunization is a major barrier to transfusion in sickle cell disease (SCD)
because it can lead to transfusion deadlock and the development of life-threatening …

Red blood cell (RBC) transfusion is a critical component of optimal management for a broad
range of conditions. Regardless of the indication, pretransfusion testing is required to …

Background While convalescent plasma (CP) may benefit patients with COVID‐19,
fundamental questions remain regarding its efficacy, including the components of CP that …

Transfusion of red blood cells (RBCs) is a life‐saving intervention for anemic patients.
Human induced pluripotent stem cells (iPSC) have the capability to expand and differentiate …

Incompatible red blood cell (RBC) transfusion can result in life-threatening transfusion
complications that can be challenging to manage in patients with transfusion-dependent …

RBC transfusion remains a cornerstone in the treatment of sickle cell disease (SCD).
However, as with many interventions, transfusion of RBCs is not without risk. Allogeneic …