Long-term survival rates after a diagnosis of breast cancer are steadily rising. This is good
news, but clinicians must also recognize that this brings new challenges to the medical …

Sarcopenia is an age-related geriatric syndrome that is characterized by a progressive loss
of muscle mass, strength and function. Chronic heart failure (CHF), the final stage of various …

On behalf of the Italian Society for Osteoporosis, Mineral Metabolism and Bone Diseases
(SIOMMMS) with the endorsement of Italian Society of Endocrinology (SIE) Italian Society of …

Medical Pharmacology & Therapeutics provides all the information medical and healthcare
students need throughout their degree programme and beyond, including for professional …

Context: GH excess causes an increase in bone turnover, but the consequences in terms of
skeletal fragility have long been uncertain due to the heterogeneity of studies dealing with …

Glucocorticoids modulate the secretion of growth hormone (GH) by various and competing
effects on the hypothalamus and pituitary gland. The final effects of this modulation depend …

Diabetes mellitus is a frequent complication of Cushing syndrome (CS) which is caused by
chronic exposure to glucocorticoid excess, either endogenous or exogenous, and that is …

An impaired glucose metabolism, which often leads to the onset of diabetes mellitus (DM), is
a common complication of chronic exposure to exogenous and endogenous glucocorticoid …

A large Canadian cohort was studied over 10 years to see if proton pump inhibitor (PPI) use
increased the risk of sustaining a fragility fracture. We found an increased risk of fracture in …

Neuroendocrinology of bone is a new area of research based on the evidence that pituitary
hormones may directly modulate bone remodeling and metabolism. Skeletal fragility …