Gallbladder cancer (GBC) is rare, but is the most malignant type of biliary tract tumor.
Unfortunately, only a small population of cancer patients is acceptable for the surgical …

Background & Aims: The diagnosis and management of Barrett's esophagus (BE) are
controversial. We conducted a critical review of the literature in BE to provide guidance on …

This book is the third volume of the 4th Edition of the WHO series on histological and genetic
typing of human tumours. It is an authoritative, concise reference book providing an …

OBJECTIVES: Most patients with Barrett's esophagus do not progress to cancer, but those
who do seem to have markedly increased survival when cancers are detected at an early …

The value of endoscopic surveillance biopsy for dysplasia and carcinoma in patients with
Barrett's esophagus is controversial. One reason is that the available histologic criteria are …

With completion of the human genome sequence, we now have our first clear look at the
target organ for neoplastic disease. However, the conceptual framework for understanding …

Background and aims: Oesophageal adenocarcinoma frequently develops on a background
of metaplastic Barrett's epithelium. The development of malignancy is accompanied by …

BACKGROUND Patients with superficial (mucosal or submucosal) esophageal carcinoma
(SEC) have significantly better survival rates than patients with advanced carcinoma. Some …

Abstract α-Methylacyl-CoA racemase (AMACR) catalyzes the racemization of α-methyl,
branched carboxylic coenzyme A thioesters, and is overexpressed in a variety of neoplasms …

BACKGROUND It has been reported that p53 regulates the G2‐M checkpoint transition
through cyclin B1, and it has been suggested that p53 plays an important role in the …