The cingulum bundle is a prominent white matter tract that interconnects frontal, parietal, and
medial temporal sites, while also linking subcortical nuclei to the cingulate gyrus. Despite its …

Alzheimer's disease (AD) is a degenerative neurological disease in elderly individuals.
Subjective cognitive decline (SCD), mild cognitive impairment (MCI) and further …

It is widely assumed that incipient protein pathology in the medial temporal lobe instigates
the loss of episodic memory in Alzheimer's disease, one of the earliest cognitive deficits in …

Intermittent hypoxia, reoxygenation, and hypercapnia or hypocapnia occur in both adults
and children during untreated apnoea and hypopnoea, along with changes in cerebral …

The uncinate fasciculus (UF) is a long-range white matter tract that connects limbic regions
in the temporal lobe to the frontal lobe. The UF is one of the latest developing tracts, and …

On the 50th anniversary of Norman Geschwind's seminal paper entitled 'Disconnexion
syndrome in animal and man', we pay tribute to his ideas by applying contemporary …

Small vessel disease is a stroke subtype characterized by pathology of the small perforating
arteries, which supply the sub-cortical structures of the brain. Small vessel disease is …

There is accumulating evidence that at current acquisition resolutions for diffusion-weighted
(DW) MRI, the vast majority of white matter voxels contains “crossing fibers”, referring to …

Brain changes associated with Alzheimer's disease (AD) begin decades before disease
diagnosis. While β-amyloid plaques and neurofibrillary tangles are defining features of AD …

Although the mammillary bodies were one of the first neural structures to be implicated in
memory, it has long been assumed that their main function was to act primarily as a …