Amyotrophic Lateral Sclerosis (ALS) is a progressive disease with prevalent mitochondrial
dysfunctions affecting both upper and lower motor neurons in the motor cortex, brainstem …

The sideroflexin (SFXN) family is a group of mitochondrial membrane proteins. Although the
function of the SFXN family in mitochondria has been widely recognized, the expression …

Background: Sideroflexins (SFXNs) are a family of highly conserved mitochondrial
transporters which regulate iron homeostasis and mitochondrial respiratory chain. However …

Iron is essential for all the lives and mitochondria integrate iron into heme and Fe-S clusters
for diverse use as cofactors. Here, we screened mitochondrial proteins in KU812 human …

Acute myeloid leukemia (AML) is a heterogeneous disease with rapid progression and
frequent mutations. Sideroflexin3 (SFXN3) has been shown to be involved in various …

The sideroflexin (SFXN) family is a group of mitochondrial membrane proteins. Although the
function of the SFXN family in mitochondria has been widely recognized, the expression …

The Sideroflexin (SFXN) family consists of five mitochondrial membrane proteins, SFXN1
through SFXN5. These proteins were initially considered mitochondrial solute carriers …

Integrating functional proteomics and next-generation sequencing (NGS) offers a
comprehensive approach to unraveling the molecular intricacies of breast cancer. This study …

Simple Summary Mitochondria are central players in cell fate and cell death. Indeed,
mitochondrial dysfunction has been observed in many diseases, including …

Abstract We identified SFXN-1.2 to regulate both morphologies as well as dynamics of
mitochondria. SFXN-1.2 is an ortholog of human Sideroflexin 1/3 associated with …