This review is focused on purinergic neurotransmission, ie, ATP released from nerves as a
transmitter or cotransmitter to act as an extracellular signaling molecule on both pre-and …

Adenosine exerts two parallel modulatory roles in the CNS, acting as a homeostatic
modulator and also as a neuromodulator at the synaptic level. We will present evidence to …

Reliable transmission of activity from nerve to muscle is necessary for the normal function of
the body. The term 'safety factor'refers to the ability of neuromuscular transmission to remain …

▪ Abstract The quantity of neurotransmitter released into the synaptic cleft, the reliability with
which it is released, and the response of the postsynaptic cell to that transmitter all contribute …

Seven P2X receptor subunits have been cloned which form functional homo-and
heterotrimers. These are cation-selective channels, equally permeable to Na+ and K+ and …

Adenosine is a potent modulator of neuronal activity throughout the nervous system.
Previous evidence suggests that adenosine presynaptically inhibits synaptic transmission …

Amyotrophic lateral sclerosis is characterized by a progressive degeneration of the
corticospinal tract motor neurons. Growing evidence suggests that degeneration may begin …

The role of adenosine and its nucleotides in central synaptic transmission - ScienceDirect Skip
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THE mammalian neuromuscular junction (NMJ) is one of the most studied and best
understood synapses. Recent work has brought forth new information as to development …

1 The effects of adenosine and various derivatives were examined in the in vitro
hippocampal slice preparation from rat. 2 The amplitudes of extracellularly recorded field …