Cell culture in microfluidic droplets
Cell manipulation in droplets has emerged as one of the great successes of microfluidic
technologies, with the development of single-cell screening. However, the droplet format has …
technologies, with the development of single-cell screening. However, the droplet format has …
Droplet-based microfluidics in biomedical applications
Droplet-based microfluidic systems have been employed to manipulate discrete fluid
volumes with immiscible phases. Creating the fluid droplets at microscale has led to a …
volumes with immiscible phases. Creating the fluid droplets at microscale has led to a …
Intelligent microfluidics: The convergence of machine learning and microfluidics in materials science and biomedicine
Microfluidics permit the automated manipulation of fluids at the microscale with high
throughput and spatiotemporal precision, enabling the generation of large, multidimensional …
throughput and spatiotemporal precision, enabling the generation of large, multidimensional …
Recent advances in manipulation of micro-and nano-objects with magnetic fields at small scales
Manipulation of micro-and nano-objects has been widely studied in the past two decades
due to its potential applications in various fields. In this review, we focus primarily on …
due to its potential applications in various fields. In this review, we focus primarily on …
Droplet microfluidics: from proof-of-concept to real-world utility?
Droplet microfluidics constitutes a diverse and practical tool set that enables chemical and
biological experiments to be performed at high speed and with enhanced efficiency when …
biological experiments to be performed at high speed and with enhanced efficiency when …
High‐precision stereolithography of biomicrofluidic devices
AP Kuo, N Bhattacharjee, YS Lee… - Advanced materials …, 2019 - Wiley Online Library
Stereolithography (SL) is emerging as an attractive alternative to soft lithography for
fabricating microfluidic devices due to its low cost and high design efficiency. Low molecular …
fabricating microfluidic devices due to its low cost and high design efficiency. Low molecular …
Ultrahigh-throughput screening enables efficient single-round oxidase remodelling
Biocatalysis provides a potentially sustainable means of chemical manufacturing. However,
the tailoring of enzymes to industrial processes is often laborious and time consuming …
the tailoring of enzymes to industrial processes is often laborious and time consuming …
Speeding up enzyme discovery and engineering with ultrahigh-throughput methods
HA Bunzel, X Garrabou, M Pott, D Hilvert - Current opinion in structural …, 2018 - Elsevier
Exploring the sequence space of enzyme catalysts is ultimately a numbers game. Ultrahigh-
throughput screening methods for rapid analysis of millions of variants are therefore …
throughput screening methods for rapid analysis of millions of variants are therefore …
Substantial Improvement of an Epimerase for the Synthesis of D‐Allulose by Biosensor‐Based High‐Throughput Microdroplet Screening
C Li, X Gao, H Qi, W Zhang, L Li, C Wei… - Angewandte …, 2023 - Wiley Online Library
Biosynthesis of D‐allulose has been achieved using ketose 3‐epimerases (KEases), but its
application is limited by poor catalytic performance. In this study, we redesigned a …
application is limited by poor catalytic performance. In this study, we redesigned a …
Intelligent acoustofluidics enabled mini-bioreactors for human brain organoids
Acoustofluidics, by combining acoustics and microfluidics, provides a unique means to
manipulate cells and liquids for broad applications in biomedical sciences and translational …
manipulate cells and liquids for broad applications in biomedical sciences and translational …