Recent advances in contrast-enhanced photoacoustic imaging: overcoming the physical and practical challenges

W Choi, B Park, S Choi, D Oh, J Kim, C Kim - Chemical Reviews, 2023 - ACS Publications
For decades now, photoacoustic imaging (PAI) has been investigated to realize its potential
as a niche biomedical imaging modality. Despite its highly desirable optical contrast and …

Recent progress in fluorescent probes for bacteria

Y Huang, W Chen, J Chung, J Yin, J Yoon - Chemical Society Reviews, 2021 - pubs.rsc.org
Food fermentation, antibiotics, and pollutant degradation are closely related to bacteria.
Bacteria play an irreplaceable role in life. However, some bacteria seriously threaten human …

Fluorescent probe strategy for live cell distinction

X Liu, YT Chang - Chemical Society Reviews, 2022 - pubs.rsc.org
Live cell discrimination is the first and essential step to understand complex biosystems.
Conventional cell discrimination involving various antibodies relies on selective surface …

Molecular sizes and antibacterial performance relationships of flexible ionic liquid derivatives

L Zheng, J Li, M Yu, W Jia, S Duan, D Cao… - Journal of the …, 2020 - ACS Publications
Cationic agents, such as ionic liquids (ILs)-based species, have broad-spectrum
antibacterial activities. However, the antibacterial mechanisms lack systematic and …

A general approach to design dual ratiometric fluorescent and photoacoustic probes for quantitatively visualizing tumor hypoxia levels in vivo

S Zhang, H Chen, L Wang, X Qin, BP Jiang… - Angewandte …, 2022 - Wiley Online Library
Herein, we describe an energy balance strategy between fluorescence and photoacoustic
effects by sulfur substitution to transform existing hemicyanine dyes (Cy) into optimized …

Microneedle patches with antimicrobial and immunomodulating properties for infected wound healing

S Li, X Wang, Z Yan, T Wang, Z Chen… - Advanced …, 2023 - Wiley Online Library
Abstract Treatment of infected wounds remains a challenge owing to antibiotic resistance;
thus, developing smart biomaterials for the healing of infected wounds is urgently needed. In …

Bacteria eat nanoprobes for aggregation-enhanced imaging and killing diverse microorganisms

Y Yang, B Chu, J Cheng, J Tang, B Song… - Nature …, 2022 - nature.com
Currently optical-based techniques for in vivo microbial population imaging are limited by
low imaging depth and highly light-scattering tissue; and moreover, are generally effective …

Precise Molecular Engineering of Type I Photosensitizers with Near‐Infrared Aggregation‐Induced Emission for Image‐Guided Photodynamic Killing of Multidrug …

P Xiao, Z Shen, D Wang, Y Pan, Y Li, J Gong… - Advanced …, 2022 - Wiley Online Library
Multidrug resistance (MDR) bacteria pose a serious threat to human health. The
development of alternative treatment modalities and therapeutic agents for treating MDR …

An Enzyme‐Activatable Aggregation‐Induced‐Emission Probe: Intraoperative Pathological Fluorescent Diagnosis of Pancreatic Cancer via Specific Cathepsin E

Z Zhu, Q Wang, X Chen, Q Wang, C Yan… - Advanced …, 2022 - Wiley Online Library
Pancreatic cancer (PC) is one of the most devastating malignant tumors. However,
fluorescence probes for early clinical diagnosis of PC often encounter difficulties in accuracy …

NIR-II bioimaging of small molecule fluorophores: From basic research to clinical applications

C Li, X Guan, X Zhang, D Zhou, S Son, Y Xu… - Biosensors and …, 2022 - Elsevier
Due to the low autofluorescence and deep-photo penetration, the second near-infrared
region fluorescence imaging technology (NIR-II, 1000–2000 nm) has been widely utilized in …