KATP Channels in the Cardiovascular System
MN Foster, WA Coetzee - Physiological reviews, 2016 - journals.physiology.org
KATP channels are integral to the functions of many cells and tissues. The use of
electrophysiological methods has allowed for a detailed characterization of KATP channels …
electrophysiological methods has allowed for a detailed characterization of KATP channels …
Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning
Therapeutic strategies to protect the ischemic myocardium have been studied extensively.
Reperfusion is the definitive treatment for acute coronary syndromes, especially acute …
Reperfusion is the definitive treatment for acute coronary syndromes, especially acute …
ATP-Sensitive potassium channels and their physiological and pathophysiological roles.
ATP sensitive potassium channels (KATP) are so named because they open as cellular ATP
levels fall. This leads to membrane hyperpolarization and thus links cellular metabolism to …
levels fall. This leads to membrane hyperpolarization and thus links cellular metabolism to …
Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia–reperfusion injury: Evidence for a role of KATP channels
Hydrogen sulfide (H 2 S) is a gaseous mediator, produced by the metabolic pathways that
regulate tissue concentrations of sulfur–containing amino acids. Recent studies indicate that …
regulate tissue concentrations of sulfur–containing amino acids. Recent studies indicate that …
Chinese herbal medicine on cardiovascular diseases and the mechanisms of action
C Liu, Y Huang - Frontiers in pharmacology, 2016 - frontiersin.org
Cardiovascular diseases are the principal cause of death worldwide. The potentially serious
adverse effects of therapeutic drugs lead to growing awareness of the role of Chinese herbal …
adverse effects of therapeutic drugs lead to growing awareness of the role of Chinese herbal …
KATP channels and preconditioning: a re-examination of the role of mitochondrial KATP channels and an overview of alternative mechanisms
PJ Hanley, J Daut - Journal of molecular and cellular cardiology, 2005 - Elsevier
Preconditioning by one or several brief periods of ischemia activates an endogenous
cardioprotective program that increases the resistance of cardiomyocytes to injury by …
cardioprotective program that increases the resistance of cardiomyocytes to injury by …
Loss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1
Aims While a wealth of data has uncovered distinct microRNA (miR) expression alterations
in hypertrophic and ischaemic/reperfused (I/R) hearts, little is known about miR regulation …
in hypertrophic and ischaemic/reperfused (I/R) hearts, little is known about miR regulation …
Cardioprotection afforded by chronic exercise is mediated by the sarcolemmal, and not the mitochondrial, isoform of the KATP channel in the rat
This study was conducted to examine the role of myocardial ATP‐sensitive potassium
(KATP) channels in exercise‐induced protection from ischaemia–reperfusion (I–R) injury …
(KATP) channels in exercise‐induced protection from ischaemia–reperfusion (I–R) injury …
Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury
GR Budas, EN Churchill, D Mochly-Rosen - Pharmacological research, 2007 - Elsevier
Current treatment for acute myocardial infarction (AMI) is aimed at limiting the duration of
ischemia by either mechanical (balloon catheters) or enzymatic (thrombolytics) means to …
ischemia by either mechanical (balloon catheters) or enzymatic (thrombolytics) means to …
Upregulation of ATP-sensitive potassium channels as the potential mechanism of cardioprotection and vasorelaxation under the action of pyridoxal-5-phosphate in old …
RB Strutynskyi, NA Strutynska… - Journal of …, 2023 - journals.sagepub.com
Background: The aging process is accompanied by the weakening of the protective systems
of the organism, in particular by the decrease in the expression of ATP-sensitive potassium …
of the organism, in particular by the decrease in the expression of ATP-sensitive potassium …