KATP channels are integral to the functions of many cells and tissues. The use of
electrophysiological methods has allowed for a detailed characterization of KATP channels …

Therapeutic strategies to protect the ischemic myocardium have been studied extensively.
Reperfusion is the definitive treatment for acute coronary syndromes, especially acute …

ATP sensitive potassium channels (KATP) are so named because they open as cellular ATP
levels fall. This leads to membrane hyperpolarization and thus links cellular metabolism to …

Hydrogen sulfide (H 2 S) is a gaseous mediator, produced by the metabolic pathways that
regulate tissue concentrations of sulfur–containing amino acids. Recent studies indicate that …

Cardiovascular diseases are the principal cause of death worldwide. The potentially serious
adverse effects of therapeutic drugs lead to growing awareness of the role of Chinese herbal …

Preconditioning by one or several brief periods of ischemia activates an endogenous
cardioprotective program that increases the resistance of cardiomyocytes to injury by …

Aims While a wealth of data has uncovered distinct microRNA (miR) expression alterations
in hypertrophic and ischaemic/reperfused (I/R) hearts, little is known about miR regulation …

This study was conducted to examine the role of myocardial ATP‐sensitive potassium
(KATP) channels in exercise‐induced protection from ischaemia–reperfusion (I–R) injury …

Current treatment for acute myocardial infarction (AMI) is aimed at limiting the duration of
ischemia by either mechanical (balloon catheters) or enzymatic (thrombolytics) means to …

Background: The aging process is accompanied by the weakening of the protective systems
of the organism, in particular by the decrease in the expression of ATP-sensitive potassium …