Cytokines and chemokines involved in osteoarthritis pathogenesis
Osteoarthritis is a common cause of disability worldwide. Although commonly referred to as
a disease of the joint cartilage, osteoarthritis affects all joint tissues equally. The …
a disease of the joint cartilage, osteoarthritis affects all joint tissues equally. The …
Knee osteoarthritis: epidemiology, pathogenesis, and mesenchymal stem cells: what else is new? An update
R Giorgino, D Albano, S Fusco, GM Peretti… - International journal of …, 2023 - mdpi.com
Osteoarthritis (OA) is a chronic disease and the most common orthopedic disorder. A vast
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …
majority of the social OA burden is related to hips and knees. The prevalence of knee OA …
The roles of matrix metalloproteinases and their inhibitors in human diseases
GA Cabral-Pacheco, I Garza-Veloz… - International journal of …, 2020 - mdpi.com
Matrix metalloproteinases (MMPs) are a family of zinc-dependent extracellular matrix (ECM)
remodeling endopeptidases that have the capacity to degrade almost every component of …
remodeling endopeptidases that have the capacity to degrade almost every component of …
The role of matrix metalloproteinases (MMP-8, MMP-9, MMP-13) in periodontal and peri-implant pathological processes
I Luchian, A Goriuc, D Sandu, M Covasa - International Journal of …, 2022 - mdpi.com
Severe periodontitis, a destructive inflammatory disease of the supporting tissues of the
teeth, ranks sixth in terms of global spread, affecting about 11% of the population …
teeth, ranks sixth in terms of global spread, affecting about 11% of the population …
Overview of MMP-13 as a promising target for the treatment of osteoarthritis
Q Hu, M Ecker - International journal of molecular sciences, 2021 - mdpi.com
Osteoarthritis (OA) is a common degenerative disease characterized by the destruction of
articular cartilage and chronic inflammation of surrounding tissues. Matrix metalloproteinase …
articular cartilage and chronic inflammation of surrounding tissues. Matrix metalloproteinase …
Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions
Y Cho, S Jeong, H Kim, D Kang, J Lee… - … & molecular medicine, 2021 - nature.com
Osteoarthritis (OA) is the most common form of arthritis. It is characterized by progressive
destruction of articular cartilage and the development of chronic pain and constitutes a …
destruction of articular cartilage and the development of chronic pain and constitutes a …
Genistein: A review on its anti-inflammatory properties
Nowadays, non-resolving inflammation is becoming a major trigger in various diseases as it
plays a significant role in the pathogenesis of atherosclerosis, asthma, cancer, obesity …
plays a significant role in the pathogenesis of atherosclerosis, asthma, cancer, obesity …
The development of disease-modifying therapies for osteoarthritis (DMOADs): the evidence to date
Osteoarthritis (OA) is a complex heterogeneous articular disease with multiple joint tissue
involvement of varying severity and no regulatory-agency-approved disease-modifying …
involvement of varying severity and no regulatory-agency-approved disease-modifying …
Injectable drug delivery systems for osteoarthritis and rheumatoid arthritis
Joint diseases are one of the most common causes of morbidity and disability worldwide.
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …
The main diseases that affect joint cartilage are osteoarthritis and rheumatoid arthritis, which …
Cartilage calcification in osteoarthritis: mechanisms and clinical relevance
I Bernabei, A So, N Busso, S Nasi - Nature Reviews Rheumatology, 2023 - nature.com
Pathological calcification of cartilage is a hallmark of osteoarthritis (OA). Calcification can be
observed both at the cartilage surface and in its deeper layers. The formation of calcium …
observed both at the cartilage surface and in its deeper layers. The formation of calcium …