Novel diagnostic biomarkers in colorectal cancer

AL Zygulska, P Pierzchalski - International journal of molecular sciences, 2022 - mdpi.com
Colorectal cancer (CRC) is still a leading cause of cancer death worldwide. Less than half of
cases are diagnosed when the cancer is locally advanced. CRC is a heterogenous disease …

[HTML][HTML] Cytokeratin 7 and cytokeratin 20 expression in cancer: a tissue microarray study on 15,424 cancers

D Dum, A Menz, C Völkel, N De Wispelaere… - … and molecular pathology, 2022 - Elsevier
Combined analysis of cytokeratin 7 (CK7) and cytokeratin 20 (CK20) is often used for
assessing the origin of metastatic cancer. To evaluate the diagnostic utility of CK7 and …

Emerging insights into keratin 7 roles in tumor progression and metastasis of cancers

H Hosseinalizadeh, QM Hussain… - Frontiers in …, 2024 - frontiersin.org
Keratin 7 (KRT7), also known as cytokeratin-7 (CK-7) or K7, constitutes the principal
constituent of the intermediate filament cytoskeleton and is primarily expressed in the simple …

Cytokeratin 7 expression as a predictor of an unfavorable prognosis in colorectal carcinoma

J Hrudka, H Fišerová, K Jelínková, R Matěj… - Scientific reports, 2021 - nature.com
Colorectal carcinoma (CRC) is associated with significant morbidity and mortality worldwide.
Cytokeratins (CKs) are widely expressed in various types of carcinomas, whereas in CRC it …

Propolis Has an Anticancer Effect on Early Stage Colorectal Cancer by Affecting Epithelial Differentiation and Gut Immunity in the Tumor Microenvironment

MH Shen, CY Liu, KW Chang, CL Lai, SC Chang… - Nutrients, 2023 - mdpi.com
Colorectal cancer (CRC) is one of the most common cancers and is the second leading
cause of cancer-related death in the world. Due to the westernization of diets, young patients …

Loss of SATB2 expression correlates with cytokeratin 7 and PD-L1 tumor cell positivity and aggressiveness in colorectal cancer

J Hrudka, R Matěj, A Nikov, I Tomyak, H Fišerová… - Scientific Reports, 2022 - nature.com
Colorectal carcinoma (CRC) is a disease that causes significant morbidity and mortality
worldwide. To improve treatment, new biomarkers are needed to allow better patient risk …

The Role of circRNA-miRNA-mRNA Regulatory Network and its Potential Biomarker Function in Colorectal Cancer

X Fu, P Chen, H Wang - Protein and Peptide Letters, 2023 - ingentaconnect.com
Background: Revealing the process and mechanism of colorectal cancer will facilitate the
discovery of new biomarkers and contribute to the development of targeted drugs …

[HTML][HTML] Diagnostic accuracy of SATB2 in identifying primary and metastatic colorectal carcinoma: a comparative immunohistochemical study

MS Elnady, FA Eltatawy, AG Nosseir… - …, 2022 - ncbi.nlm.nih.gov
Special AT-rich sequence-binding protein 2 (SATB2) is a new marker that could identify the
colonic origin, but whether its expression is preserved in metastatic colorectal carcinomas …

Immunophenotypic comparison of neoplasms of the appendix, right colon, and left colon in search of a site-specific phenotypic signature

H Mesa, JC Manivel, WS Larson… - … journal of surgical …, 2020 - journals.sagepub.com
Aims. The proximal colon derives from the midgut endoderm, the distal one third derives
from the hindgut endoderm, and the distal anal canal is of ectodermal origin. At least 5 …

[HTML][HTML] Long-Term Survival in Metastatic Pancreatic Adenocarcinoma of Intestinal Type

G Rahnea-Nita, LF Rebegea, VT Grigorean… - Journal of Clinical …, 2024 - mdpi.com
Introduction and Literature Review: Pancreatic cancer is often diagnosed in an
advanced/metastatic stage, as it is a very aggressive type of cancer. The prognosis of …