The application of mesenchymal stromal cells (MSCs) and their derivative exosome in skin wound healing: a comprehensive review
Recently, mesenchymal stromal cells (MSCs) and also their exosome has become a game-
changing tool in the context of tissue engineering and regenerative medicine. MSCs due to …
changing tool in the context of tissue engineering and regenerative medicine. MSCs due to …
Three-dimensional spheroids as in vitro preclinical models for cancer research
Most cancer biologists still rely on conventional two-dimensional (2D) monolayer culture
techniques to test in vitro anti-tumor drugs prior to in vivo testing. However, the vast majority …
techniques to test in vitro anti-tumor drugs prior to in vivo testing. However, the vast majority …
Strategies for 3D bioprinting of spheroids: A comprehensive review
Biofabricated tissues have found numerous applications in tissue engineering and
regenerative medicine in addition to the promotion of disease modeling and drug …
regenerative medicine in addition to the promotion of disease modeling and drug …
Advances in Spheroids and Organoids on a Chip
Multicellular spheroids and organoids are promising in vitro 3D models in personalized
medicine and drug screening. They replicate the structural and functional characteristics of …
medicine and drug screening. They replicate the structural and functional characteristics of …
Effects of mesenchymal stem cell‐derived paracrine signals and their delivery strategies
Mesenchymal stem cells (MSCs) have been widely studied as a versatile cell source for
tissue regeneration and remodeling due to their potent bioactivity, which includes …
tissue regeneration and remodeling due to their potent bioactivity, which includes …
Three-dimensional spheroid culture of human mesenchymal stem cells: offering therapeutic advantages and in vitro glimpses of the in vivo state
BL Yen, CC Hsieh, PJ Hsu, CC Chang… - Stem cells …, 2023 - academic.oup.com
As invaluable as the standard 2-dimensional (2D) monolayer in vitro cell culture system has
been, there is increasing evidence that 3-dimensional (3D) non-adherent conditions are …
been, there is increasing evidence that 3-dimensional (3D) non-adherent conditions are …
Biomaterials that promote cell-cell interactions enhance the paracrine function of MSCs
Mesenchymal stromal cells (MSCs) secrete paracrine factors that play crucial roles during
tissue regeneration. Whether this paracrine function is influenced by the properties of …
tissue regeneration. Whether this paracrine function is influenced by the properties of …
The tumor-on-chip: Recent advances in the development of microfluidic systems to recapitulate the physiology of solid tumors
G Trujillo-de Santiago, BG Flores-Garza… - Materials, 2019 - mdpi.com
The ideal in vitro recreation of the micro-tumor niche—although much needed for a better
understanding of cancer etiology and development of better anticancer therapies—is highly …
understanding of cancer etiology and development of better anticancer therapies—is highly …
Specificity of 3D MSC spheroids microenvironment: impact on MSC behavior and properties
A Jauković, D Abadjieva, D Trivanović… - Stem cell reviews and …, 2020 - Springer
Mesenchymal stem cells (MSC) have been considered the promising candidates for the
regenerative and personalized medicine due to their self-renewal potential, multilineage …
regenerative and personalized medicine due to their self-renewal potential, multilineage …
Pretreated mesenchymal stem cells and their secretome: enhanced immunotherapeutic strategies
Y Su, C Xu, W Cheng, Y Zhao, L Sui… - International journal of …, 2023 - mdpi.com
Mesenchymal stem cells (MSCs) with self-renewing, multilineage differentiation and
immunomodulatory properties, have been extensively studied in the field of regenerative …
immunomodulatory properties, have been extensively studied in the field of regenerative …