iDNA-ABF: multi-scale deep biological language learning model for the interpretable prediction of DNA methylations

J Jin, Y Yu, R Wang, X Zeng, C Pang, Y Jiang, Z Li… - Genome biology, 2022 - Springer
In this study, we propose iDNA-ABF, a multi-scale deep biological language learning model
that enables the interpretable prediction of DNA methylations based on genomic sequences …

4mCBERT: A computing tool for the identification of DNA N4-methylcytosine sites by sequence-and chemical-derived information based on ensemble learning …

S Yang, Z Yang, J Yang - International Journal of Biological …, 2023 - Elsevier
Abstract N4-methylcytosine (4mC) is an important DNA chemical modification pattern which
is a new methylation modification discovered in recent years and plays critical roles in gene …

[HTML][HTML] DeepSF-4mC: A deep learning model for predicting DNA cytosine 4mC methylation sites leveraging sequence features

Z Yao, F Li, W Xie, J Chen, J Wu, Y Zhan, X Wu… - Computers in Biology …, 2024 - Elsevier
Abstract N 4-methylcytosine (4mC) is a DNA modification involving the addition of a methyl
group to the fourth nitrogen atom of the cytosine base. This modification may influence gene …

DNA-MP: a generalized DNA modifications predictor for multiple species based on powerful sequence encoding method

M Nabeel Asim, M Ali Ibrahim, A Fazeel… - Briefings in …, 2023 - academic.oup.com
Accurate prediction of deoxyribonucleic acid (DNA) modifications is essential to explore and
discern the process of cell differentiation, gene expression and epigenetic regulation …

Mouse4mC-BGRU: Deep learning for predicting DNA N4-methylcytosine sites in mouse genome

J Jin, Y Yu, L Wei - Methods, 2022 - Elsevier
Abstract DNA N4-methylcytosine (4mC) is an important DNA modification and plays a crucial
role in a variety of biological processes. Accurate 4mC site identification is fundamental to …

Systematic analysis and accurate identification of DNA N4-methylcytosine sites by deep learning

L Yu, Y Zhang, L Xue, F Liu, Q Chen, J Luo… - Frontiers in …, 2022 - frontiersin.org
DNA N4-methylcytosine (4mC) is a pivotal epigenetic modification that plays an essential
role in DNA replication, repair, expression and differentiation. To gain insight into the …

PrUb-EL: A hybrid framework based on deep learning for identifying ubiquitination sites in Arabidopsis thaliana using ensemble learning strategy

H Wang, H Li, W Gao, J Xie - Analytical Biochemistry, 2022 - Elsevier
Identification of ubiquitination sites is central to many biological experiments. Ubiquitination
is a kind of post-translational protein modification (PTM). It is a key mechanism for increasing …

Multi-scale DNA language model improves 6 mA binding sites prediction

A Hou, H Luo, H Liu, L Luo, P Ding - Computational Biology and Chemistry, 2024 - Elsevier
DNA methylation at the N6 position of adenine (N6-methyladenine, 6 mA), which refers to
the attachment of a methyl group to the N6 site of the adenine (A) of DNA, is an important …

Accurate prediction of anti-hypertensive peptides based on convolutional neural network and gated recurrent unit

H Shi, S Zhang - Interdisciplinary Sciences: Computational Life …, 2022 - Springer
Hypertension (HT) is a general disease, and also one of the most ordinary and major causes
of cardiovascular disease. Some diseases are caused by high blood pressure, including …

[HTML][HTML] 4mC-CGRU: Identification of N4-Methylcytosine (4mC) sites using convolution gated recurrent unit in Rosaceae genome

A Sultana, SJ Mitu, MN Pathan, MN Uddin… - … Biology and Chemistry, 2023 - Elsevier
An epigenetic modification is DNA N4-methylcytosine (4mC) that affects several biological
functions without altering the DNA nucleotides, including DNA conformation, cell …