Abstract Development of central nervous system (CNS) is regulated by both intrinsic and
peripheral signals. Previous studies have suggested that environmental factors affect …

Neurodevelopment is a complex process governed by both intrinsic and extrinsic signals.
While historically studied by researching the brain, inputs from the periphery impact many …

The barrier between the blood and the ventricular cerebrospinal fluid (CSF) is located at the
choroid plexuses. At the interface between two circulating fluids, these richly vascularized …

The gut microbiome has a tremendous influence on human physiology, including the
nervous system. During fetal development, the initial colonization of the microbiome …

Background Epilepsy is a common and debilitating consequence of traumatic brain injury
(TBI). Seizures contribute to progressive neurodegeneration and poor functional and …

The mechanisms underlying Zika virus (ZIKV)-related microcephaly and other
neurodevelopment defects remain poorly understood. Here, we describe the derivation and …

In this narrative review, a theoretical framework on the crosstalk between physical exercise
and blood-brain barrier (BBB) permeability is presented. We discuss the influence of …

Prenatal stress (PS) has been linked to abnormal cognitive, behavioral and psychosocial
outcomes in both animals and humans. Animal studies have clearly demonstrated PS effects …

1. The blood–brain barrier is essential for the maintenance and regulation of the neural
microenvironment. The main characteristic features of blood–brain barrier endothelial cells …

1. Ion permeability of the blood‐brain barrier was studied by in situ measurement of
transendothelial electrical resistance in anaesthetized rats aged between 17 days gestation …