In spite of significant progress towards malaria control and elimination achieved in South
America in the 2000s, this mosquito-transmitted tropical disease remains an important public …

The complexity of host–pathogen interactions often leads to distinct clinical outcomes upon
infection with different pathogen strains. In this Review, we explore the interactions between …

Effective malaria control strategies require an accurate understanding of the epidemiology of
locally transmitted Plasmodium species. Compared to Plasmodium falciparum infection …

Trypanosoma cruzi, Trypanosoma brucei and Leishmania (Trypanosomatidae:
Kinetoplastida) are parasitic protozoan causing Chagas disease, African Trypanosomiasis …

Trypomastigote forms of Trypanosoma cruzi, the causative agent of Chagas Disease, shed
extracellular vesicles (EVs) enriched with glycoproteins of the gp85/trans-sialidase (TS) …

Glycomics has become an increasingly important field of research since glycans play critical
roles in biology processes ranging from molecular recognition and signaling to cellular …

Initiatives to eradicate malaria have a good impact on P. falciparum malaria worldwide. P.
vivax, however, still presents significant difficulties. This is due to its unique biological traits …

Background After a marked reduction in malaria burden in Cambodia over the last decades,
case numbers increased again in 2017–2018. In light of the national goal of malaria …

Introduction Chagas disease (CD) affects~ 7 million people worldwide. Benznidazole (BZN)
and nifurtimox (NFX) are the only approved drugs for CD chemotherapy. Although both …

Trypanosoma cruzi, the aetiologic agent of Chagas disease, releases vesicles containing a
wide range of surface molecules known to affect the host immunological responses and the …