The HSPA2 gene is a poorly characterized member of the HSPA (HSP70) family. HSPA2
was originally described as testis-specific and expressed at the highest level in pachytene …

DNA-damage-induced phospho-signaling has been studied for decades, with a focus
mainly on initiation of the signaling cascade, and the kinases activated by DNA lesions. It is …

Protein phosphorylation is a critical regulatory mechanism in cellular signalling. To this end,
PP1 is a major eukaryotic serine/threonine-specific phosphatase whose cellular functions, in …

In mammals, testicular Heat shock-related 70 kDa protein 2 (HSPA2) is a chaperon strictly
linked to spermatogenesis status, whereas its presence in spermatozoa ensures successful …

Bolting is a key process in the growth and development of lettuce (Lactuca sativa L.). A high
temperature can induce early bolting, which decreases both the quality and production of …

Mammalian spermatogenesis is characterised by dramatic cellular change to transform the
non‐polar spermatogonium into a highly polarised and functional spermatozoon. The …

The major post-translational modification in eukaryotes is protein phosphorylation which
mediates responses to signals in a myriad of cellular processes. Not surprisingly, many …

Spermatogenesis is the process by which terminally differentiated sperm are produced from
male germline stem cells. This complex developmental process requires the coordination of …

The posttranslational modification of histones is crucial in spermatogenesis, as in other
tissues; however, during spermiogenesis, histones are replaced with protamines, which are …

Background The unicellular parasite Trypanosoma cruzi is the causative agent of Chagaś
disease in humans. Adherence of the infective stage to elements of the extracellular matrix …