HIV–host cell interactions
SK Masenga, BC Mweene, E Luwaya, L Muchaili… - Cells, 2023 - mdpi.com
The development of antiretroviral drugs (ARVs) was a great milestone in the management of
HIV infection. ARVs suppress viral activity in the host cell, thus minimizing injury to the cells …
HIV infection. ARVs suppress viral activity in the host cell, thus minimizing injury to the cells …
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
Programmed cell death protein 1 (PD-1) is an immune checkpoint receptor that is
upregulated on activated T cells for the induction of immune tolerance,. Tumour cells …
upregulated on activated T cells for the induction of immune tolerance,. Tumour cells …
Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19
Our understanding of protective versus pathological immune responses to SARS-CoV-2, the
virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of …
virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of …
Hematopoietic responses to SARS-CoV-2 infection
S Elahi - Cellular and Molecular Life Sciences, 2022 - Springer
Under physiological conditions, hematopoietic stem and progenitor cells (HSPCs) in the
bone marrow niches are responsible for the highly regulated and interconnected …
bone marrow niches are responsible for the highly regulated and interconnected …
A single-cell atlas of liver metastases of colorectal cancer reveals reprogramming of the tumor microenvironment in response to preoperative chemotherapy
LH Che, JW Liu, JP Huo, R Luo, RM Xu, C He, YQ Li… - Cell discovery, 2021 - nature.com
Metastasis is the primary cause of cancer-related mortality in colorectal cancer (CRC)
patients. How to improve therapeutic options for patients with metastatic CRC is the core …
patients. How to improve therapeutic options for patients with metastatic CRC is the core …
A novel angiotensin-converting enzyme (ACE) inhibitory peptide from tilapia skin: Preparation, identification and its potential antihypertensive mechanism
Y Dong, W Yan, YQ Zhang, ZY Dai - Food Chemistry, 2024 - Elsevier
To obtain food-derived peptides with high ACE inhibitory activity, tilapia skin was pretreated
with steam explosion prior to enzymatic hydrolysis. The results showed that steam explosion …
with steam explosion prior to enzymatic hydrolysis. The results showed that steam explosion …
Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts
Background The success of agents that reverse T-cell inhibitory signals, such as anti-PD-
1/PD-L1 therapies, has reinvigorated cancer immunotherapy research. However, since only …
1/PD-L1 therapies, has reinvigorated cancer immunotherapy research. However, since only …
[HTML][HTML] CD4-transgenic zebrafish reveal tissue-resident Th2-and regulatory T cell–like populations and diverse mononuclear phagocytes
CT Dee, RT Nagaraju, EI Athanasiadis… - The Journal of …, 2016 - journals.aai.org
CD4+ T cells are at the nexus of the innate and adaptive arms of the immune system.
However, little is known about the evolutionary history of CD4+ T cells, and it is unclear …
However, little is known about the evolutionary history of CD4+ T cells, and it is unclear …
Identification of a humanized mouse model for functional testing of immune-mediated biomaterial foreign body response
Biomedical devices comprise a major component of modern medicine, however immune-
mediated fibrosis and rejection can limit their function over time. Here, we describe a …
mediated fibrosis and rejection can limit their function over time. Here, we describe a …
Imaging mass cytometry reveals the prominent role of myeloid cells at the maternal-fetal interface
Although the immunological complexity of the maternal-fetal interface is well appreciated,
the actual interaction of maternal immune cells and fetal trophoblasts is insufficiently …
the actual interaction of maternal immune cells and fetal trophoblasts is insufficiently …