Cannabis has a long history of anecdotal medicinal use and limited licensed medicinal use.
Until recently, alleged clinical effects from anecdotal reports and the use of licensed …

Background: The smoke generated from cannabis delivers biologically active cannabinoids
and a number of combustion-derived toxins, both of which raise questions regarding the …

Cannabidiol (CBD) is part of a group of phytocannabinoids derived from Cannabis sativa.
Initial work on CBD presumed the compound was inactive, but it was later found to exhibit …

The endocannabinoid system (ECS) exerts a modulatory effect of important functions such
as neurotransmission, glial activation, oxidative stress, or protein homeostasis …

Background Cannabinoids including cannabidiol have recognized genotoxic activities but
their significance has not been studied broadly epidemiologically across the teratological …

Background Cannabidiol (CBD) has demonstrated anti-inflammatory, analgesic, anxiolytic
and neuroprotective effects that have the potential to benefit athletes. This pilot study …

The therapeutic potential of Cannabis sativa has been recognized since ancient times.
Phytocannabinoids, endocannabinoids and synthetic cannabinoids activate two major G …

Cannabis and cannabinoids are implicated in multiple genotoxic, epigenotoxic and
chromosomal-toxic mechanisms and interact with several morphogenic pathways, likely …

Abnormal energy metabolism, as one of the important hallmarks of cancer, was induced by
multiple carcinogenic factors and tumor-specific microenvironments. It comprises aerobic …

Abstract Objectives Antiepileptic drugs (AEDs) exhibit adverse and beneficial effects on
mitochondria, which have a strong impact on the treatment of patients with a mitochondrial …