Insulin resistance and diabetes mellitus in Alzheimer's disease

J Burillo, P Marqués, B Jiménez, C González-Blanco… - Cells, 2021 - mdpi.com
Type 2 diabetes mellitus is a progressive disease that is characterized by the appearance of
insulin resistance. The term insulin resistance is very wide and could affect different proteins …

Diabetes and cognitive impairment: a role for glucotoxicity and dopaminergic dysfunction

FC Pignalosa, A Desiderio, P Mirra, C Nigro… - International journal of …, 2021 - mdpi.com
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by hyperglycemia,
responsible for the onset of several long-term complications. Recent evidence suggests that …

Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder

CU Correll, J Detraux, J De Lepeleire… - World …, 2015 - Wiley Online Library
People with severe mental illness have a considerably shorter lifespan than the general
population. This excess mortality is mainly due to physical illness. Next to mental illness …

[HTML][HTML] Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care

M De Hert, CU Correll, J Bobes… - World …, 2011 - ncbi.nlm.nih.gov
The lifespan of people with severe mental illness (SMI) is shorter compared to the general
population. This excess mortality is mainly due to physical illness. We report prevalence …

Dopamine outside the brain: The eye, cardiovascular system and endocrine pancreas

C Bucolo, GM Leggio, F Drago, S Salomone - Pharmacology & …, 2019 - Elsevier
Dopamine (DA) and DA receptors (DR) have been extensively studied in the central nervous
system (CNS), but their role in the periphery is still poorly understood. Here we summarize …

Antipsychotic drugs: from receptor-binding profiles to metabolic side effects

S Siafis, D Tzachanis, M Samara… - Current …, 2018 - ingentaconnect.com
Background: Antipsychotic-induced metabolic side effects are major concerns in
psychopharmacology and clinical psychiatry. Their pathogenetic mechanisms are still not …

Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors

D Aslanoglou, S Bertera, M Sánchez-Soto… - Translational …, 2021 - nature.com
Dopamine (DA) and norepinephrine (NE) are catecholamines primarily studied in the central
nervous system that also act in the pancreas as peripheral regulators of metabolism …

Immunomodulatory effects mediated by dopamine

R Arreola, S Alvarez-Herrera… - Journal of …, 2016 - Wiley Online Library
Dopamine (DA), a neurotransmitter in the central nervous system (CNS), has modulatory
functions at the systemic level. The peripheral and central nervous systems have …

Board-invited review: St. Anthony's Fire in livestock: causes, mechanisms, and potential solutions

JR Strickland, ML Looper, JC Matthews… - Journal of animal …, 2011 - academic.oup.com
After a brief history of ergot alkaloids and ergotism, this review focuses on the metabolism
and mechanisms of action of the ergot alkaloids. The authors provide models of how these …

Diabetes mellitus and severe mental illness: mechanisms and clinical implications

RIG Holt, AJ Mitchell - Nature Reviews Endocrinology, 2015 - nature.com
The prevalence of diabetes mellitus is twofold to threefold higher in people with severe
mental illness (SMI) than in the general population, with diabetes mellitus affecting∼ 12% of …