Methotrexate (MTX) is still one of the gold standard treatments for rheumatoid arthritis (RA). It
shows diverse outcomes in blood level and clinical response, this was demonstrated by its …

Abstract Interleukin-37 (IL-37) is a new anti-inflammatory cytokine that inhibits
immunological response and inflammation. The purpose of this study is to look into the role …

Introduction: Parvovirus B19 virus-mediated viral inflammation and immune-complex
deposition generate mainly short-term manifestations in the affected individuals. The …

Abstract Background: Toll-like receptors (TLRs) play a significant role in the activation of
adaptive immunity and may have an essential role in the development of rheumatoid arthritis …

Rheumatoid arthritis (RA) can cause permanent joint damage and disability through
inflammation in the joints. Other organs, such as blood vessels, lungs, heart, eyes and skin …

Rheumatoid arthritis (RA) is a chronic autoimmune disorder that activates arthritogenic
immune responses, along with many of the systemic inflammatory cascades that result in …

Background: Rheumatoid arthritis (RA) is a lifelong autoimmune inflammatory disease of
unknown origin. An early diagnosis of RA could improve the outcome. Several …

Ghrelin and leptin are two hormones that possess multiple functions, including appetite
regulation, maintenance of the tissue homeostasis and regulation of proinflammatory …

Background: Obesity is abnormal accumulation of fat in the body, which led to many health
problems that will reduce the life expectancy. Arthritis is joints inflammation that cause many …

Background: MicroRNAs are gene expression regulators, associated with several human
pathologies. Rheumatoid arthritis (RA) is an autoimmune systemic disease characterised by …