Treatment optimization in MS: Canadian MS Working Group updated recommendations

MS Freedman, D Selchen, DL Arnold, A Prat… - Canadian Journal of …, 2013 - cambridge.org
The Canadian Multiple Sclerosis Working Group (CMSWG) developed practical
recommendations in 2004 to assist clinicians in optimizing the use of disease-modifying …

Association of chronic active multiple sclerosis lesions with disability in vivo

M Absinta, P Sati, F Masuzzo, G Nair, V Sethi… - JAMA …, 2019 - jamanetwork.com
Importance In multiple sclerosis (MS), chronic active lesions, which previously could only be
detected at autopsy, can now be identified on susceptibility-based magnetic resonance …

Towards a global view of multiple sclerosis genetics

BM Jacobs, M Peter, G Giovannoni, AJ Noyce… - Nature Reviews …, 2022 - nature.com
Multiple sclerosis (MS) is a neuroimmunological disorder of the CNS with a strong heritable
component. The genetic architecture of MS susceptibility is well understood in populations of …

Disability in multiple sclerosis: a reference for patients and clinicians

I Kister, E Chamot, AR Salter, GR Cutter, TE Bacon… - Neurology, 2013 - AAN Enterprises
Objective: To create a reference table of disability outcomes in multiple sclerosis (MS) that
would enable patients to rank their disability relative to others' with similar disease duration …

Age related multiple sclerosis severity score: disability ranked by age

A Manouchehrinia, H Westerlind… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Background: The Multiple Sclerosis Severity Score (MSSS) is obtained by normalising the
Expanded Disability Status Scale (EDSS) score for disease duration and has been a …

Multiple sclerosis in US minority populations: clinical practice insights

O Khan, MJ Williams, L Amezcua, A Javed… - Neurology: Clinical …, 2015 - AAN Enterprises
The heterogeneity of multiple sclerosis (MS) characteristics among various ethnic minority
populations is a topic of recent interest. However, these populations are consistently …

Brain and retinal atrophy in African-Americans versus Caucasian-Americans with multiple sclerosis: a longitudinal study

NG Caldito, S Saidha, ES Sotirchos, BE Dewey… - Brain, 2018 - academic.oup.com
Abstract On average, African Americans with multiple sclerosis demonstrate higher
inflammatory disease activity, faster disability accumulation, greater visual dysfunction, more …

Hispanic Americans and African Americans with multiple sclerosis have more severe disease course than Caucasian Americans

RE Ventura, AO Antezana, T Bacon… - Multiple Sclerosis …, 2017 - journals.sagepub.com
Whether disease course in Hispanic Americans (HA) with multiple sclerosis (MS) is different
from Caucasian Americans (CA) or African Americans (AA) is unknown. We compared MS …

Gut microbiome of treatment-naïve MS patients of different ethnicities early in disease course

RE Ventura, T Iizumi, T Battaglia, M Liu… - Scientific reports, 2019 - nature.com
Although the intestinal microbiome has been increasingly implicated in autoimmune
diseases, much is unknown about its roles in Multiple Sclerosis (MS). Our aim was to …

How multiple sclerosis symptoms vary by age, sex, and race/ethnicity

I Kister, T Bacon, GR Cutter - Neurology: Clinical Practice, 2021 - AAN Enterprises
Objective Little is known about how symptom severity in the various neurologic domains
commonly affected by multiple sclerosis (MS) varies by age, sex, and race/ethnicity. Methods …