A comprehensive analysis and anti-cancer activities of quercetin in ROS-mediated cancer and cancer stem cells
Reactive oxygen species (ROS) induce carcinogenesis by causing genetic mutations,
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
[HTML][HTML] Advanced implications of nanotechnology in disease control and environmental perspectives
Nanotechnology encompasses a wide range of devices derived from biology, engineering,
chemistry, and physics, and this scientific field is composed of great collaboration among …
chemistry, and physics, and this scientific field is composed of great collaboration among …
Enzymes and enzymatic mechanisms in enzymatic degradation of lignocellulosic biomass: A mini-review
Enzymatic hydrolysis is the key step limiting the efficiency of the biorefinery of lignocellulosic
biomass. Enzymes involved in enzymatic hydrolysis and their interactions with biomass …
biomass. Enzymes involved in enzymatic hydrolysis and their interactions with biomass …
[HTML][HTML] Point-specific interactions of isovitexin with the neighboring amino acid residues of the hACE2 receptor as a targeted therapeutic agent in suppressing the …
Objective: Despite the development of several vaccines against severe acute respiratory
syndrome coronavirus-2, the need for an additional prophylactic agent is evident. In recent …
syndrome coronavirus-2, the need for an additional prophylactic agent is evident. In recent …
Oncoinformatic screening of the gene clusters involved in the HER2-positive breast cancer formation along with the in silico pharmacodynamic profiling of selective …
The HER2-positive patients occupy~ 30% of the total breast cancer patients globally where
no prevalent drugs are available to mitigate the frequent metastasis clinically except …
no prevalent drugs are available to mitigate the frequent metastasis clinically except …
Natural flavonoids effectively block the CD81 receptor of hepatocytes and inhibit HCV infection: A computational drug development approach
Hepatitis C virus (HCV) infection is a major public health concern, and almost two million
people are infected per year globally. This is occurred by the diverse spectrum of viral …
people are infected per year globally. This is occurred by the diverse spectrum of viral …
Unraveling the mechanisms underlying lignin and xylan dissolution in recyclable biphasic catalytic systems
Despite the exceptional performance of recyclable biphasic pretreatment systems (ie, p-
toluenesulfonic acid (TsOH)/pentanol, H 2 SO 4/butanol, and AlCl 3/MTHF) in the holistic …
toluenesulfonic acid (TsOH)/pentanol, H 2 SO 4/butanol, and AlCl 3/MTHF) in the holistic …
Target-specificity of different amyrin subunits in impeding HCV influx mechanism inside the human cells considering the quantum tunnel profiles and molecular strings …
HCV is a hepatotropic RNA virus recognized for its frequent virulence and fatality worldwide.
Despite many vaccine development programs underway, researchers are on a quest for …
Despite many vaccine development programs underway, researchers are on a quest for …
Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development …
An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
Molecular Dynamics Simulation and Pharmacoinformatic Integrated Analysis of Bioactive Phytochemicals from Azadirachta indica (Neem) to Treat Diabetes Mellitus
A Abdullah, P Biswas, M Sahabuddin… - Journal of …, 2023 - Wiley Online Library
Diabetes mellitus is a chronic hormonal and metabolic disorder in which our body cannot
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
generate necessary insulin or does not act in response to it, accordingly, ensuing in …