Growth and division of the peptidoglycan matrix
PDA Rohs, TG Bernhardt - Annual review of microbiology, 2021 - annualreviews.org
Most bacteria are surrounded by a peptidoglycan cell wall that defines their shape and
protects them from osmotic lysis. The expansion and division of this structure therefore plays …
protects them from osmotic lysis. The expansion and division of this structure therefore plays …
The bacterial cell wall: from lipid II flipping to polymerization
The peptidoglycan (PG) cell wall is an extra-cytoplasmic glycopeptide polymeric structure
that protects bacteria from osmotic lysis and determines cellular shape. Since the cell wall …
that protects bacteria from osmotic lysis and determines cellular shape. Since the cell wall …
Cryo-EM structure of the bacterial divisome core complex and antibiotic target FtsWIQBL
L Käshammer, F van den Ent, M Jeffery, NL Jean… - Nature …, 2023 - nature.com
In most bacteria, cell division relies on the synthesis of new cell wall material by the
multiprotein divisome complex. Thus, at the core of the divisome are the transglycosylase …
multiprotein divisome complex. Thus, at the core of the divisome are the transglycosylase …
β-Lactams against the Fortress of the Gram-Positive Staphylococcus aureus Bacterium
JF Fisher, S Mobashery - Chemical reviews, 2020 - ACS Publications
The biological diversity of the unicellular bacteria—whether assessed by shape, food,
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …
metabolism, or ecological niche—surely rivals (if not exceeds) that of the multicellular …
Peptidoglycan: structure, synthesis, and regulation
Peptidoglycan is a defining feature of the bacterial cell wall. Initially identified as a target of
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …
the revolutionary beta-lactam antibiotics, peptidoglycan has become a subject of much …
[HTML][HTML] Limits and barriers to adaptation to climate variability and change in Bangladeshi coastal fishing communities
Limits and barriers to adaptation restrict people's ability to address the negative impacts of
climate change or manage risks in a way that maximises their wellbeing. There is a lack of …
climate change or manage risks in a way that maximises their wellbeing. There is a lack of …
A conserved subcomplex within the bacterial cytokinetic ring activates cell wall synthesis by the FtsW-FtsI synthase
LS Marmont, TG Bernhardt - Proceedings of the National …, 2020 - National Acad Sciences
Cell division in bacteria is mediated by a multiprotein assembly called the divisome. A major
function of this machinery is the synthesis of the peptidoglycan (PG) cell wall that caps the …
function of this machinery is the synthesis of the peptidoglycan (PG) cell wall that caps the …
Intrinsically disordered protein regions are required for cell wall homeostasis in Bacillus subtilis
Intrinsically disordered protein regions (IDRs) have been implicated in diverse nuclear and
cytoplasmic functions in eukaryotes, but their roles in bacteria are less clear. Here, we report …
cytoplasmic functions in eukaryotes, but their roles in bacteria are less clear. Here, we report …
Structural basis of lipopolysaccharide maturation by the O-antigen ligase
The outer membrane of Gram-negative bacteria has an external leaflet that is largely
composed of lipopolysaccharide, which provides a selective permeation barrier, particularly …
composed of lipopolysaccharide, which provides a selective permeation barrier, particularly …
Emerging structural insights into C-type glycosyltransferases
JAN Alexander, KP Locher - Current Opinion in Structural Biology, 2023 - Elsevier
Glycosyltransferases of the C superfamily (GT-Cs) are enzymes found in all domains of life.
They catalyse the stepwise synthesis of oligosaccharides or the transfer of assembled …
They catalyse the stepwise synthesis of oligosaccharides or the transfer of assembled …