Current state of Alzheimer's fluid biomarkers

JL Molinuevo, S Ayton, R Batrla, MM Bednar… - Acta …, 2018 - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disease with a complex and
heterogeneous pathophysiology. The number of people living with AD is predicted to …

Mechanisms of ferritinophagy and ferroptosis in diseases

S Li, P Huang, F Lai, T Zhang, J Guan, H Wan… - Molecular …, 2024 - Springer
The discovery of the role of autophagy, particularly the selective form like ferritinophagy, in
promoting cells to undergo ferroptosis has inspired us to investigate functional connections …

Ferrosenescence: the iron age of neurodegeneration?

A Sfera, K Bullock, A Price, L Inderias… - Mechanisms of ageing and …, 2018 - Elsevier
Aging has been associated with iron retention in many cell types, including the neurons,
promoting neurodegeneration by ferroptosis. Excess intracellular iron accelerates aging by …

A diagnostic index based on quantitative susceptibility mapping and voxel-based morphometry may improve early diagnosis of Alzheimer's disease

R Sato, K Kudo, N Udo, M Matsushima, I Yabe… - European …, 2022 - Springer
Objectives Voxel-based morphometry (VBM) is widely used to quantify the progression of
Alzheimer's disease (AD), but improvement is still needed for accurate early diagnosis. We …

[HTML][HTML] 靶向铁死亡和铁自噬: 心血管疾病的新靶点?

栾一, 杨阳, 栾莹, 刘慧, 邢晗, 裴金燕… - … 版)(B 辑: 生物医学和 …, 2023 - jzusb.zjujournals.com
心血管疾病(CVDs) 在全球范围内是死亡的主要驱动因素. 铁是一种必需的微量元素,
在多种生物过程中很重要. 几十年来, 铁对心血管疾病的作用引起了广泛的讨论 …

Exploring iron deposition patterns using light and electron microscopy in the mouse brain across aging and Alzheimer's disease pathology conditions

V Lau, J VanderZwaag, C Murray, MÈ Tremblay - 2024 - researchsquare.com
Alzheimer's disease (AD) involves cognitive decline, possibly via multiple concurrent
pathologies associated with iron accumulation. To investigate if iron accumulation in AD is …

Aging and Alzheimer's Disease: Multimodal Investigation of Image-derived Biomarkers

S Moallemian - 2023 - orbi.uliege.be
Aging is an inevitable process in life and the primary risk factor for most neurodegenerative
diseases including Alzheimer's disease (AD), the most common form of dementia. As life …

[PDF][PDF] Healthy aging and Alzheimer's

MJ Betts, V Perosa, D Hämmerer, E Düzel - 2023 - researchgate.net
The use of magnetic resonance imaging (MRI) biomarkers is an important mainstay in the
assessment of neurodegeneration in aging and Alzheimer's disease (AD) dementia both in …