Deep brain stimulation (DBS) treatment has proven effective in suppressing symptoms of
rigidity, bradykinesia, and tremor in Parkinson's disease. Still, patients may suffer from …

Introduction The globus pallidus internus (GPi) region has evolved as a potential target for
deep brain stimulation (DBS) in Parkinson's disease (PD). DBS of the GPi (GPi DBS) is an …

Globus pallidus internus deep brain stimulation is an established therapy for patients with
medication-refractory Parkinson's disease. Clinical outcomes are highly dependent on …

Exaggerated subthalamic beta oscillatory activity and increased beta range cortico-
subthalamic synchrony have crystallized as the electrophysiological hallmarks of …

Over the past three decades, deep brain stimulation (DBS) for Parkinson's disease (PD) has
been applied in a continuous open loop fashion, unresponsive to changes in a given …

Motor symptoms of Parkinson's Disease (PD) are associated with dopamine deficits and
pathological oscillation of basal ganglia (BG) neurons in the β range ([12-30] Hz). However …

Subthalamotomy using transcranial magnetic resonance-guided focused ultrasound
(tcMRgFUS) is a novel and promising treatment for Parkinson's Disease (PD). In this study …

To elucidate the role of the basal ganglia during REM sleep movements in Parkinson's
disease (PD) we recorded pallidal neural activity from four PD patients. Unlike …

Sleep disturbances, specifically decreases in total sleep time and sleep efficiency as well as
increased sleep onset latency and wakefulness after sleep onset, are highly prevalent in …

Background Preserved cycling capabilities in patients with Parkinson's disease, especially
in those with freezing of gait are still poorly understood. Previous research with invasive …