The role of microRNA in the pathogenesis of diabetic nephropathy
J Szostak, A Gorący, D Durys, P Dec… - International Journal of …, 2023 - mdpi.com
Diabetic nephropathy is one of the most common and severe complications of diabetes
mellitus, affecting one in every five patients suffering from diabetes. Despite extensive …
mellitus, affecting one in every five patients suffering from diabetes. Despite extensive …
NLRP3-mediated pyroptosis in diabetic nephropathy
J Wan, D Liu, S Pan, S Zhou, Z Liu - Frontiers in pharmacology, 2022 - frontiersin.org
Diabetic nephropathy (DN) is the main cause of end-stage renal disease (ESRD), which is
characterized by a series of abnormal changes such as glomerulosclerosis, podocyte loss …
characterized by a series of abnormal changes such as glomerulosclerosis, podocyte loss …
Total Flavones of Abelmoschus manihot Ameliorates Podocyte Pyroptosis and Injury in High Glucose Conditions by Targeting METTL3-Dependent m6A Modification …
BH Liu, Y Tu, GX Ni, J Yan, L Yue, ZL Li… - Frontiers in …, 2021 - frontiersin.org
Background: The total flavones of Abelmoschus manihot (TFA), a compound that is extracted
from Abelmoschus manihot, has been widely used in China to reduce podocyte injury in …
from Abelmoschus manihot, has been widely used in China to reduce podocyte injury in …
MicroRNAs in diabetic nephropathy: from molecular mechanisms to new therapeutic targets of treatment
A Yarahmadi, SZ Shahrokhi, Z Mostafavi-Pour… - Biochemical …, 2021 - Elsevier
Despite considerable investigation in diabetic nephropathy (DN) pathogenesis and possible
treatments, current therapies still do not provide competent prevention from disease …
treatments, current therapies still do not provide competent prevention from disease …
Exosomes from mesenchymal stem cells expressing microribonucleic acid-125b inhibit the progression of diabetic nephropathy via the tumour necrosis factor receptor …
X Cai, F Zou, R Xuan, XY Lai - Endocrine Journal, 2021 - jstage.jst.go.jp
Diabetic nephropathy (DN) seriously threatens the health of patients with diabetes.
Moreover, it has been reported that mesenchymal stem cell (MSC)-derived exosomal …
Moreover, it has been reported that mesenchymal stem cell (MSC)-derived exosomal …
Bioinformatic reconstruction and analysis of gene networks related to glucose variability in diabetes and its complications
OV Saik, VV Klimontov - International Journal of Molecular Sciences, 2020 - mdpi.com
Glucose variability (GV) has been recognized recently as a promoter of complications and
therapeutic targets in diabetes. The aim of this study was to reconstruct and analyze gene …
therapeutic targets in diabetes. The aim of this study was to reconstruct and analyze gene …
Metformin mediates MicroRNA-21 regulated circulating matrix metalloproteinase-9 in diabetic nephropathy: an in-silico and clinical study
Metformin is commonly used as an oral hypoglycaemic agent in type 2 diabetes mellitus
(T2DM). MicroRNA-21 is widely studied in diabetic and diabetic nephropathy (DN) patients …
(T2DM). MicroRNA-21 is widely studied in diabetic and diabetic nephropathy (DN) patients …
Polyphenols target miRNAs as a therapeutic strategy for diabetic complications
F Malakoti, E Mohammadi, M Akbari Oryani… - Critical Reviews in …, 2024 - Taylor & Francis
MiRNAs are a large group of non-coding RNAs which participate in different cellular
pathways like inflammation and oxidation through transcriptional, post-transcriptional, and …
pathways like inflammation and oxidation through transcriptional, post-transcriptional, and …
The association of dietary insulinemic indices with PI3K, PTEN, and Akt gene expressions in visceral and subcutaneous adipose tissues among individuals …
H Ahmadirad, F Teymoori, H Farhadnejad… - Frontiers in …, 2024 - frontiersin.org
Background/objective The current study investigates the association between dietary
insulinemic indices and Akt, PTEN, and PI3K gene expressions in visceral adipose tissue …
insulinemic indices and Akt, PTEN, and PI3K gene expressions in visceral adipose tissue …
[HTML][HTML] Novel molecular networks and regulatory microRNAs in type 2 diabetes mellitus: multiomics integration and interactomics study
M Khokhar, D Roy, S Tomo, A Gadwal… - JMIR Bioinformatics …, 2022 - bioinform.jmir.org
Background: Type 2 diabetes mellitus (T2DM) is a metabolic disorder with severe
comorbidities. A multiomics approach can facilitate the identification of novel therapeutic …
comorbidities. A multiomics approach can facilitate the identification of novel therapeutic …