Evaluation of left atrial size and function: relevance for clinical practice

L Thomas, D Muraru, BA Popescu, M Sitges… - Journal of the American …, 2020 - Elsevier
Highlights•The LA is emerging as a biomarker for evaluation of diastolic dysfunction, AF, and
HFpEF.•LA size, although routinely evaluated by 2DE, may be more accurately evaluated by …

Left atrial strain for assessment of left ventricular diastolic function: focus on populations with normal LVEF

SF Nagueh, SU Khan - Cardiovascular Imaging, 2023 - jacc.org
Left atrial (LA) strain has emerged as a useful parameter for the assessment of left
ventricular (LV) diastolic function and the estimation of LV filling pressures. Some have …

[HTML][HTML] Innate immune memory after brain injury drives inflammatory cardiac dysfunction

A Simats, S Zhang, D Messerer, F Chong, S Beşkardeş… - Cell, 2024 - cell.com
The medical burden of stroke extends beyond the brain injury itself and is largely
determined by chronic comorbidities that develop secondarily. We hypothesized that these …

Clinical importance of left atrial infiltration in cardiac transthyretin amyloidosis

F Bandera, R Martone, L Chacko… - Cardiovascular …, 2022 - jacc.org
Objectives The aim of this study was to characterize left atrial (LA) pathology in explanted
hearts with transthyretin amyloid cardiomyopathy (ATTR-CM); LA mechanics using …

Association of left atrial structure and function with heart failure in older adults

RM Inciardi, B Claggett, M Minamisawa, SH Shin… - Journal of the American …, 2022 - jacc.org
Background Limited data exist to characterize novel measures of left atrial (LA) structure and
function in older adults without prevalent heart failure (HF). Objectives The aim was to …

How to do LA strain

JU Voigt, GG Mălăescu, K Haugaa… - European Heart …, 2020 - academic.oup.com
Modern speckle tracking allows the assessment of atrial strain in the clinic. The approach is
new, lacks standardization and the user might encounter several problems in its routine use …

Left atrial strain determinants during the cardiac phases

GG Mălăescu, O Mirea, R Capotă, AM Petrescu… - Cardiovascular …, 2022 - jacc.org
Objectives The present study investigated the determinants of left atrial (LA) strain in all
phases of the cardiac cycle. Background LA strain by speckle-tracking echocardiography …

Prevention of Pathological Atrial Remodeling and Atrial Fibrillation: JACC State-of-the-Art Review

YC Chen, A Voskoboinik, AL Gerche… - Journal of the American …, 2021 - jacc.org
Atrial enlargement in response to pathological stimuli (eg, hypertension, mitral valve
disease) and physiological stimuli (exercise, pregnancy) can be comparable in magnitude …

Left atrial disease and left atrial reverse remodelling across different stages of heart failure development and progression: a new target for prevention and treatment

RM Inciardi, A Bonelli… - European Journal of …, 2022 - Wiley Online Library
The left atrium is a dynamic chamber with peculiar characteristics. Stressors and disease
mechanisms may deeply modify its structure and function, leading to left atrial remodelling …

Imaging of the left atrium: pathophysiology insights and clinical utility

OA Smiseth, T Baron, PN Marino… - European Heart …, 2022 - academic.oup.com
Left atrial imaging and detailed knowledge of its pathophysiology, especially in the context
of heart failure, have become an increasingly important clinical and research focus. This …