Beta-thalassemia major patients are treated with repeated blood transfusions, which may
cause iron overload, which in turn may induce immune aberrations, and show an increased …

Background Beta-thalassemia major patients are at increased risk of complications
including endocrinopathies and bone disease due to iron overload. So, this study aimed to …

Background: Disturbance of calcium hemostasis is common in patients of ß-thalassemia
major. The objectives of this study were to determine the frequency, distribution and …

Bone disorders and disturbed calcium (Ca) homeostasis are common disorders in β-
thalassaemia major (β-TM). In the present study, two bone related markers are studied in β …

Thalassemia is an inherited disorder of autosomal recessive gene disorder caused by
impaired synthesis of one or more globin chains. The impairment alters production of …

Background: Thalassemia is a genetic disorder of defective hemoglobin synthesis. In
transfusion dependent thalassemia (TDT), iron overload is caused by repeated blood …

Introduction: Thalassemia is a rare hereditary condition that causes hemoglobin synthesis
deficiency. Recurrent blood transfusion in transfusion-dependent thalassemia (TDT) …

β-thalassemia is a genetic disorder affecting chromosome 16, inherited from one or both
parents. In spite of the improved treatment of the hematological disorder and its …

Background: Children with thalassemia major need regular blood transfusions to survive.
These multiple transfusions put them at risk for iron overload, which result in organ damage …

Background: In transfusion dependent thalassemic (TDT) patients regular blood transfusion
leads to iron overload. This increased iron is deposited in the tissue of various system and …