Achalasia is a rare disorder of the oesophageal smooth muscle characterized by impaired
relaxation of the lower oesophageal sphincter (LES) and absent or spastic contractions in …

Dysphagia is a common symptom with significant impact on quality of life. Our diagnostic
armamentarium was primarily limited to endoscopy and barium esophagram until the advent …

Background Eosinophilic oesophagitis (EoE) is an increasingly common cause of dysphagia
in both children and adults, as well as one of the most prevalent oesophageal diseases with …

METHODS: Five hundred thirty-nine adult patients who completed FLIP and HRM with a
conclusive CCv4. 0 diagnosis were included in the primary analysis. Thirty-five …

Abstract The Chicago Classification v4. 0 (CCv4. 0) is the updated classification scheme for
esophageal motility disorders using metrics from high‐resolution manometry (HRM). A key …

Gastroesophageal reflux disease (GERD) is one of the most frequent gastrointestinal
disorders. Proton pump inhibitors (PPIs) are effective in healing lesions and improving …

Background & Aims An association of eosinophilic esophagitis (EoE) with esophageal
dysmotility has been described, however, the related mechanism remains unclear. We …

Esophageal hypomotility disorders manifest with abnormal esophageal body contraction
vigor, breaks in peristaltic integrity, or failure of peristalsis in the context of normal lower …

Abstract Background and Aims This study aimed to systematically evaluate a classification
scheme of secondary peristalsis using functional luminal imaging probe (FLIP) panometry …

Nearly all patients with systemic sclerosis (SSc) are negatively affected by dysfunction in the
gastrointestinal tract, and the severity of gastrointestinal disease in SSc correlates with high …