Benzodiazepines in Alzheimer's disease: beneficial or detrimental effects

HM Al-Kuraishy, AI Al-Gareeb, HM Saad… - …, 2023 - Springer
Dementia is considered a clinical syndrome characterized by cognitive dysfunction and
memory loss. Alzheimer's disease (AD) is the most common type of dementia. AD is linked …

Understanding neuropsychiatric symptoms in Alzheimer's disease: challenges and advances in diagnosis and treatment

A Pless, D Ware, S Saggu, H Rehman… - Frontiers in …, 2023 - frontiersin.org
Neuropsychiatric symptoms (NPS) in Alzheimer's disease (AD) affect up to 97% of AD
patients, with an estimated 80% of current AD patients experiencing these symptoms …

Insights on benzodiazepines' potential in Alzheimer's disease

HM Al-Kuraishy, AI Al-Gareeb, AA Alsayegh… - Life Sciences, 2023 - Elsevier
Alzheimer's disease (AD) is the most frequent type of dementia characterized by the
deposition of amyloid beta (Aβ) plaque and tau-neurofibrillary tangles (TNTs) in the brain …

Associations of sleep disorders with all-cause MCI/dementia and different types of dementia–clinical evidence, potential pathomechanisms and treatment options: A …

G Mayer, H Frohnhofen, M Jokisch… - Frontiers in …, 2024 - frontiersin.org
Due to worldwide demographic change, the number of older persons in the population is
increasing. Aging is accompanied by changes of sleep structure, deposition of beta-amyloid …

Recent advances in understanding of sleep disorders and disturbances for dementia risk and prevention

A Lam, S Kong, SL Naismith - Current Opinion in Psychiatry, 2024 - journals.lww.com
Recent work examining the pathophysiological links between sleep and dementia is
strongest for obstructive sleep apnoea and sleep duration, while findings in insomnia …

Benzodiazepine Use and the Risk of Dementia in the Elderly Population: An Umbrella Review of Meta-Analyses

CC Wu, MH Liao, CH Su, TN Poly, MC Lin - Journal of Personalized …, 2023 - mdpi.com
The prevalence of dementia among the elderly is high, and it is the leading cause of death
globally. However, the relationship between benzodiazepine use and dementia risk has …

Benzodiazepine use and risk of incident MCI and dementia in a community sample

EG Teverovsky, A Gildengers, X Ran… - International …, 2024 - cambridge.org
Objectives: Older adults commonly take benzodiazepines (BZDs) that may have long-term
adverse cognitive effects. We investigated whether BZD use was related to developing mild …

Optimising the use of electronic medical records for large scale research in psychiatry

D Newby, N Taylor, DW Joyce… - Translational Psychiatry, 2024 - nature.com
The explosion and abundance of digital data could facilitate large-scale research for
psychiatry and mental health. Research using so-called “real world data”—such as …

Benzodiazepine-receptor agonist utilization in outpatients with anxiety disorder: a retrospective study based on electronic healthcare data from a large general tertiary …

D Liu, Q Zhang, Z Zhao, M Chen, Y Hou, G Wang… - Healthcare, 2023 - mdpi.com
Benzodiazepine-receptor agonists (BZRAs), including benzodiazepines (BZDs) and drugs
related to BZDs (Z-drugs), are commonly used for anxiety, but often have side effects. We …

Sleep disturbances and dementia in older adults

T Kawada - American Journal of Preventive Medicine, 2023 - ajpmonline.org
In the June 2023 issue of the American Journal of Preventive Medicine, Wong et al. 1
conducted a prospective study to examine the association between sleep disturbances …