The indole scaffold is found in a wide range of bioactive heterocycles and natural products.
Moreover, the indole moiety is considered as the active principle in several alkaloids such …

Indoles are amongst the most essential class of heteroaromatics in organic chemistry, being
commonly found in biologically active natural products. Indole and its derivatives have …

Spirooxindolo-pyrrolidine, pyrrolizine and pyrrolothiazole hybrid compounds were obtained
in excellent yields from the regio-and stereoselective reaction between β-nitrostyrenes and …

Background: The indole framework is considered as one of the privileged structures in the
area of medicinal chemistry and drug discovery because compounds containing this …

In the recent years, microwave (MW) radiation is widely used as a source of heating in
organic synthesis. Since the discovery of the MW heating approach, MW-assisted reaction …

A facile 1, 3-dipolar cycloaddition of azomethine ylide generated in situ from the reaction of
1, 3-thiazolane-4-carboxylic acid and isatin to 2-arylidene-1, 3-indanediones furnished …

Three new series of 4-hydroxy-8-trifluoromethyl-quinoline derivatives were synthesized
through multi step reactions. All the newly synthesized compounds were characterized by …

Indole, an aza-heterocyclic scaffold, has been found one of the most privileged scaffolds in
heterocyclic chemistry and drug discovery. Efforts have been made to provide the complete …

Tuberculosis (TB) is still a major health concern worldwide. The increasing incidences of
multi-drug-resistant tuberculosis (MDR-TB) necessitate the development of new anti-TB …

A series of thirty eight novel 3-(4-((substituted-1H-1, 2, 3-triazol-4-yl) methyl) piperazin-1-
yl/1, 4-diazepan-1-yl) benzo [d] isoxazole and 1-(4-(benzo [d] isoxazol-3-yl) piperazin-1-yl/1 …