Colorectal cancer (CRC) is a predominant life‐threatening cancer, with liver and peritoneal
metastases as the primary causes of death. Intestinal inflammation, a known CRC risk factor …

Colorectal cancer (CRC) is one of the most lethal and prevalent solid malignancies
worldwide. There is a great need of accelerating the development and diagnosis of CRC …

A hallmark feature of tumorigenesis is uncontrolled cell division. Autophagy is regulated by
more than 30 genes and it is one of several mechanisms by which cells maintain …

At present, it is necessary to identify specific biochemical, molecular, and genetic markers
that can reliably aid in screening digestive cancer and correlate with the degree of disease …

Highly conserved nuclear protein High Mobility Group Box1 (HMGB1) present in mammals
has functionality as an immuno-modulator in the form of cytokine molecule, as a nuclear …

High-mobility group box 1 (HMGB1) is an abundant protein in most eukaryocytes. It can bind
to several receptors such as advanced glycation end products (RAGE) and Toll-like …

Background: MiR-34a is identified as a tumor suppressor gene and involved in acute
myeloid leukemia (AML) development. However, the regulatory mechanism of miR-34a in …

Abstract Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1), originally
described as a prognostic biomarker remarkably linked with metastasis potential in lung …

Colorectal cancer (CRC) results from the accumulation of both genetic and epigenetic
alterations of the genome. However, also the formation of an inflammatory milieu plays a …

The complicated stepwise lysosomal degradation process known as autophagy is in charge
of destroying and eliminating damaged organelles and defective cytoplasmic components …