Lab‐on‐a‐Contact Lens: Recent Advances and Future Opportunities in Diagnostics and Therapeutics

Y Zhu, S Li, J Li, N Falcone, Q Cui, S Shah… - Advanced …, 2022 - Wiley Online Library
The eye is one of the most complex organs in the human body, containing rich and critical
physiological information (eg, intraocular pressure, corneal temperature, and pH) as well as …

Gene therapy strategies for glaucoma from IOP reduction to retinal neuroprotection: progress towards non-viral systems

A Hakim, B Guido, L Narsineni, DW Chen… - Advanced drug delivery …, 2023 - Elsevier
Glaucoma is the result of the gradual death of retinal ganglion cells (RGCs) whose axons
form the optic nerve. Elevated intraocular pressure (IOP) is a major risk factors …

[HTML][HTML] Pathologically high intraocular pressure disturbs normal iron homeostasis and leads to retinal ganglion cell ferroptosis in glaucoma

F Yao, J Peng, E Zhang, D Ji, Z Gao, Y Tang… - Cell Death & …, 2023 - nature.com
Glaucoma can result in retinal ganglion cell (RGC) death and permanently damaged vision.
Pathologically high intraocular pressure (ph-IOP) is the leading cause of damaged vision …

[HTML][HTML] Normal and glaucomatous outflow regulation

TS Acott, JA Vranka, KE Keller, VK Raghunathan… - Progress in retinal and …, 2021 - Elsevier
Glaucoma remains only partially understood, particularly at the level of intraocular pressure
(IOP) regulation. Trabecular meshwork (TM) and Schlemm's canal inner wall endothelium …

Explainable framework for Glaucoma diagnosis by image processing and convolutional neural network synergy: analysis with doctor evaluation

O Deperlioglu, U Kose, D Gupta, A Khanna… - Future Generation …, 2022 - Elsevier
Glaucoma causes blindness in long-time untreated cases. So, its early diagnosis is very
important. Moving from that, there have been lots of Deep Learning oriented studies to …

A review on albumin as a biomaterial for ocular drug delivery

R Tiwari, NK Sethiya, AS Gulbake, NK Mehra… - International Journal of …, 2021 - Elsevier
Abstract Development of ocular drug delivery system is one of the most technically
challenging tasks, when compared with other routes of drug delivery. Eye (an intricate …

[HTML][HTML] Conventional glaucoma implants and the new MIGS devices: a comprehensive review of current options and future directions

ICF Pereira, R van de Wijdeven, HM Wyss… - Eye, 2021 - nature.com
Glaucoma is a progressive optic neuropathy that is the second leading cause of preventable
blindness worldwide, after cataract formation. A rise in the intraocular pressure (IOP) is …

[HTML][HTML] Therapeutic drugs and devices for tackling ocular hypertension and glaucoma, and need for neuroprotection and cytoprotective therapies

NA Sharif - Frontiers in pharmacology, 2021 - frontiersin.org
Damage to the optic nerve and the death of associated retinal ganglion cells (RGCs) by
elevated intraocular pressure (IOP), also known as glaucoma, is responsible for visual …

[HTML][HTML] Targeting the gut–eye axis: An emerging strategy to face ocular diseases

LIM Campagnoli, A Varesi, A Barbieri… - International Journal of …, 2023 - mdpi.com
The human microbiota refers to a large variety of microorganisms (bacteria, viruses, and
fungi) that live in different human body sites, including the gut, oral cavity, skin, and eyes. In …

Surgical outcomes of prolene gonioscopy-assisted transluminal trabeculotomy in patients with moderate to advanced open-angle glaucoma

Z Aktas, AY Ucgul, C Bektas, SS Karamert - Journal of glaucoma, 2019 - journals.lww.com
Purpose: The aim of the study was to assess the outcomes of GATT in eyes with moderate to
advanced open-angle glaucoma. Patients and Methods: A retrospective study included 104 …