[HTML][HTML] Terpene synthases as metabolic gatekeepers in the evolution of plant terpenoid chemical diversity

PS Karunanithi, P Zerbe - Frontiers in plant science, 2019 - frontiersin.org
Terpenoids comprise tens of thousands of small molecule natural products that are widely
distributed across all domains of life. Plants produce by far the largest array of terpenoids …

Understanding the biosyntheses and stress response mechanisms of aroma compounds in tea (Camellia sinensis) to safely and effectively improve tea aroma

L Zeng, N Watanabe, Z Yang - Critical reviews in food science and …, 2019 - Taylor & Francis
Metabolite formation is a biochemical and physiological feature of plants developed as an
environmental response during the evolutionary process. These metabolites help defend …

[HTML][HTML] Cytochrome P450 enzymes: a driving force of plant diterpene diversity

U Bathe, A Tissier - Phytochemistry, 2019 - Elsevier
In plant terpene biosynthesis, oxidation of the hydrocarbon backbone produced by terpene
synthases is typically carried out by cytochrome P450 oxygenases (CYPs). The …

[HTML][HTML] Image to insight: exploring natural products through mass spectrometry imaging

Y Dong, A Aharoni - Natural product reports, 2022 - pubs.rsc.org
Covering: 2017 to 2022 Mass spectrometry imaging (MSI) has become a mature molecular
imaging technique that is well-matched for natural product (NP) discovery. Here we present …

Synthetic Biology of Cannabinoids and Cannabinoid Glucosides in Nicotiana benthamiana and Saccharomyces cerevisiae

T Gülck, JK Booth, Â Carvalho… - Journal of Natural …, 2020 - ACS Publications
Phytocannabinoids are a group of plant-derived metabolites that display a wide range of
psychoactive as well as health-promoting effects. The production of pharmaceutically …

Progress and prospect: Biosynthesis of plant natural products based on plant chassis

J Lin, X Yin, Y Zeng, X Hong, S Zhang, B Cui… - Biotechnology …, 2023 - Elsevier
Plant-derived natural products are a specific class of active substances with numerous
applications in the medical, energy, and industrial fields. Many of these substances are in …

Recent progress and new perspectives for diterpenoid biosynthesis in medicinal plants

Z Hu, X Liu, M Tian, Y Ma, B Jin, W Gao… - Medicinal Research …, 2021 - Wiley Online Library
Abstract Diterpenoids, including more than 18,000 compounds, represent an important class
of metabolites that encompass both phytohormones and some industrially relevant …

[HTML][HTML] Tandemly duplicated CYP82Ds catalyze 14-hydroxylation in triptolide biosynthesis and precursor production in Saccharomyces cerevisiae

Y Zhang, J Gao, L Ma, L Tu, T Hu, X Wu, P Su… - Nature …, 2023 - nature.com
Triptolide is a valuable multipotent antitumor diterpenoid in Tripterygium wilfordii, and its C-
14 hydroxyl group is often selected for modification to enhance both the bioavailability and …

[HTML][HTML] Plant (di) terpenoid evolution: from pigments to hormones and beyond

Z Wang, DR Nelson, J Zhang, X Wan… - Natural product reports, 2023 - pubs.rsc.org
Covering: up to 2014–2022. Diterpenoid biosynthesis in plants builds on the necessary
production of (E, E, E)-geranylgeranyl diphosphate (GGPP) for photosynthetic pigment …

Stimulatory effect of dietary chasteberry (Vitex agnus-castus) extract on immunity, some immune-related gene expression, and resistance against Aeromonas …

M Rashmeei, SPH Shekarabi, MS Mehrgan… - Fish & shellfish …, 2020 - Elsevier
Chasteberry is highly recommended as an herbal medicine across the globe for treating of
many gynaecological disorders. In this study, chasteberry extract (CBE) was supplemented …