Co-transduction of dual-adeno-associated virus vectors in the neonatal and adult mouse utricles

ZR Chen, JY Guo, L He, S Liu, JY Xu… - Frontiers in Molecular …, 2022 - frontiersin.org
Adeno-associated virus (AAV)-mediated gene transfer is an efficient method of gene over-
expression in the vestibular end organs. However, AAV has limited usefulness for delivering …

Occlusion of two semicircular canals does not disrupt normal hearing in adult mice

T Wang, H Liu, DZ He, Y Li - Frontiers in neurology, 2022 - frontiersin.org
Vertigo is a debilitating disease affecting 15–20% of adults worldwide. Vestibular peripheral
vertigo is the most common cause of vertigo, often due to Meniere's disease and benign …

Precise genetic control of ATOH1 enhances maturation of regenerated hair cells in the mature mouse utricle

A Cheng, T Wang, T Yang, G Pregernig, R McCarthy… - 2023 - researchsquare.com
Vestibular hair cells are mechanoreceptors critical for detecting head position and motion. In
mammals, hair cell loss causes vestibular dysfunction as spontaneous regeneration is …

Mammalian Hair Cell Regeneration

R Taylor, A Forge - Hair Cell Regeneration, 2023 - Springer
In adult mammals, there is no hair cell regeneration in the cochlea and a limited capacity in
the vestibular organs. Research in this area is directed toward uncovering a latent potential …

[引用][C] ATOH1 相关的毛细胞再生新进展

刘宇昕, 段清川, 张杰 - 中华耳科学杂志, 2023