Hypertrophic cardiomyopathy (HCM) is a common cardiac condition caused primarily by
sarcomeric protein mutations with several distinct phenotypes, ranging from asymmetric …

Personalised medicine and the development of a virtual human or a digital twin comprises
visions of the future of medicine. To realise these innovations, an understanding of the …

Background Abnormal global longitudinal strain (GLS) has been independently associated
with adverse cardiac outcomes in both obstructive and nonobstructive hypertrophic …

Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity. We
investigated the molecular basis of the cardiac phenotype in two mouse models at …

Background We aimed to clarify the sex differences in various cardiovascular and non-
cardiovascular outcomes, and to investigate whether sex differences in outcomes are …

Background: Gender-related differences in phenotypic expression and outcomes have been
established in many cardiac conditions; however, the impact of gender in hypertrophic …

Background Alcohol septal ablation (ASA) has been proven to reverse left ventricular (LV)
remodeling in hypertrophic cardiomyopathy (HCM). However, there are no studies on the …

Background Hypertrophic cardiomyopathy (HCM) is recognized as the most prevalent form
of genetic cardiomyopathy, and recent investigations have shed light on the existence of sex …

Background It is still unclear whether there is a sex difference in the prognosis of patients
with hypertrophic cardiomyopathy (HCM). Therefore, we performed a meta‐analysis to …

Background Hypertrophic cardiomyopathy (HCM) patients have a high incidence of atrial
fibrillation (AF) and increased stroke risk, even with low CHA 2 DS 2-VASc (congestive heart …